2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate

Base Information

Chemical Name:2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate
CAS No.:1001067-09-9
Molecular Formula:C₈H₁₄N₄O₄Si
Molecular Weight:258.309
Hs Code.:
Mol file:1001067-09-9.mol

Synonyms:2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate

Suppliers and Price of 2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
100mg
$ 75.00

TCI Chemical
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate >98.0%(T)
1g
$ 127.00

TCI Chemical
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate >98.0%(T)
5g
$ 435.00

Crysdot
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 95+%
5g
$ 367.00

Chemenu
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 95%
5g
$ 347.00

American Custom Chemicals Corporation
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 95.00%
1G
$ 212.42

Ambeed
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 98%
5g
$ 181.00

Ambeed
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 98%
1g
$ 53.00

Ambeed
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 98%
250mg
$ 20.00

Alichem
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
5g
$ 400.00

Total 16 raw suppliers

Chemical Property of 2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate

Chemical Property:

Solubility.:Sol organics (CH2Cl2, THF, CH3CN, EtOAc); reacts with amines.

Purity/Quality:

97% ^*data from raw suppliers

2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Physical properties Mp (dec.) 85–86 °C.
Uses 2-(Trimethylsilyl)ethoxycarbonyl (Teoc) group is one of the most useful protecting groups for amines, which can be cleaved by fluoride ion under neutral conditions. However, 2-(trimethylsilyl)ethyl chloroformate(Teoc-Cl), which is generally used for the introduction of the Teoc protecting group in amines, is quite unstable and easy to decompose; therefore, distillation is recommended at regular intervals. On the other hand, Teoc-NT is a highly stable, nonhygroscopic crystalline material and can be stored for long periods without decomposition. Generally, carbamate formation proceeds quickly under neutral conditions, and highly pure carbamates are obtained without tedious column chromatographic purification. Furthermore, the coproduct 3-nitro-1,2,4-triazole (NT) can be recycled. It participates in the reactions of Reactions with Amines and Aminoalcohols, Amine Protection for Nucleosides, Reaction with Alcohols, etc.

Technology Process of 2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate

There total 1 articles about 2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%