Chloramine-T trihydrate

Base Information

• Chemical Name: Chloramine-T trihydrate
• CAS No.: 7080-50-4
• Molecular Formula: C7H7ClNNaO2S^.3(H2O)
• Molecular Weight: 281.693
• Hs Code.: 29350090
• Mol file: 7080-50-4.mol

Synonyms:Benzenesulfonamide,N-chloro-4-methyl-, sodium salt, trihydrate (9CI);Sodium,(N-chloro-p-toluenesulfonamido)-, trihydrate (8CI);Benzenesulfonamide,N-chloro-4-methyl-, sodium salt, hydrate (1:1:3);Tosylchloramide sodium trihydrate;

Chemical Property of Chloramine-T trihydrate

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Melting Point: 167-170 °C(lit.)
• PKA: pK1:4.54(+1) (25°C)
• Flash Point: 92 °C
• PSA: 70.21000
• Density: 1.43
• LogP: 3.09910
• Storage Temp.: 0-6°C
• Sensitive.: Moisture Sensitive
• Solubility.: H2O: passes test
• Water Solubility.: Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.

Purity/Quality:

99% ^*data from raw suppliers

Chloramine T trihydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-31-34-42
• Safety Statements: 22-26-36/37/39-45-7

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Chloramine-T trihydrate can be used for detection of bromate and halogens. Detection of bromate and halogens. Source of halonium ions and nitrogen anions in organic synthesis. Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).

Technology Process of Chloramine-T trihydrate

There total 2 articles about Chloramine-T trihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

toluene-4-sulfonamide (70-55-3) → chloramine T trihydrate (7080-50-4)

Guidance literature:

With calcium hydroxide; Chlorierung und Umsetzung des etnstandenen Calciumsalzes mit Natriumchlorid;

Reference yield:

N,N-dichloro-p-toluenesulfonamide (473-34-7) → chloramine T trihydrate (7080-50-4)

Guidance literature:

With sodium hydroxide; water;

Reference yield: 87.0%

3-methyl-2-butenyl 4,6-O-(S)-benzylidene-β-D-galactopyranoside (1221234-31-6) + chloramine T trihydrate (7080-50-4) → 3-methyl-2,3-[N-(4-methylbenzenesulfonyl)imino]butyl 4,6-O-(S)-benzylidene-β-D-galactopyranoside

Guidance literature:

With phenyltrimethylammonium tribromide; In acetonitrile; at -20 ℃; for 12h; stereoselective reaction;

DOI:10.1016/j.ejmech.2013.10.020

upstream raw materials:

N,N-dichloro-p-toluenesulfonamide

toluene-4-sulfonamide

Downstream raw materials:

acetaldehyde

butylarsonic acid

4-methylphenylarsonic acid

diphenylarsinic acid