2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Base Information

Chemical Name:2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
CAS No.:956296-81-4
Molecular Formula:C₁₄H₁₁NO₄
Molecular Weight:257.246
Hs Code.:
Mol file:956296-81-4.mol

Synonyms:2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Suppliers and Price of 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylicAcid
250mg
$ 1390.00

Medical Isotopes, Inc.
2-(4-Methoxyphenyl)-4H-furo[3,2-β]pyrrole-5-carboxylicAcid
25 mg
$ 675.00

Total 2 raw suppliers

Chemical Property of 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Chemical Property:

Melting Point:190-193°C
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(4-Methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic Acid is an intermediate in the synthesis of near-IR fluorescent dyes.

Technology Process of 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

There total 6 articles about 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 956296-80-3
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester

: 956296-81-4
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 1h; Heating;
DOI:10.1021/ja077756j

Reference yield: 90.0%

: C₁₅H₁₃NO₄

: 956296-81-4
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 1h; Inert atmosphere; Reflux;
DOI:10.1021/jacs.7b07887

Reference yield:

: 1899-24-7
5-bromo-2-furancarboxaldehyde

: 956296-81-4
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate; palladium / ethanol; toluene / 80 °C / Inert atmosphere

2: sodium methylate / ethanol / 0 °C / Inert atmosphere

3: sodium hydroxide / ethanol / Reflux

With sodium methylate; sodium carbonate; palladium; sodium hydroxide; In ethanol; toluene;
DOI:10.1021/ol2014076