956296-80-3

Usage

Uses

Used in Fluorescent Dye Synthesis:
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester is used as an intermediate in the synthesis of near-IR fluorescent dyes for various applications. Its unique molecular structure allows for the development of dyes with specific properties, such as high photostability, strong absorption, and emission in the near-IR region.
Used in Bioimaging and Diagnostics:
In the field of bioimaging and diagnostics, 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester is used as a component in the development of near-IR fluorescent probes. These probes can be used for in vivo imaging, allowing for the visualization of biological processes and the detection of diseases at a cellular level.
Used in Photodynamic Therapy:
2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester can also be used in the development of photosensitizers for photodynamic therapy (PDT). Near-IR fluorescent dyes have the advantage of deeper tissue penetration and reduced background autofluorescence, making them suitable for targeted cancer treatments.
Used in Material Science:
In material science, 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester can be used in the development of advanced materials with near-IR fluorescence properties. These materials can be applied in various fields, such as optoelectronics, sensors, and security inks.
Overall, 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester is a versatile intermediate with a wide range of applications in various industries, including bioimaging, diagnostics, photodynamic therapy, and material science. Its unique properties make it a valuable compound for the development of innovative products and technologies.

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 5720-07-0 4-methoxyphenylboronic acid 
• 637-81-0 ethyl-2-azidoacetate 
• 34070-33-2 5-(4-methoxyphenyl)furan-2-carbaldehyde 
• 956296-79-0 ethyl 2-azido-3-[5-(4-methoxyphenyl)-furan-2-yl]acrylate 

Downstream Products

• 956296-81-4 2-(4-methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid 

Relevant academic research and scientific papers

RESIN COMPOSITION AND MOLDED ARTICLE

The invention contains a resin and a near infrared fluorescent material which is one type or two or more types of compounds selected from General Formulas (I1) to (I4) and has a maximum fluorescence wavelength of 650 nm or longer. In Formulas, Ra and Rb, Rc and Rd, Rh and Ri, and Rj and Rk form rings together with the nitrogen atom to which Ra, Rc, Rh, and Rj are bonded; Re and Rf represent a halogen atom or an oxygen atom; each of Rl, Rm, Rn, and Ro independently represents a halogen atom, a C1-20 alkyl group, a C1-20 alkoxy group, an aryl group, or a heteroaryl group; Rg, Rr, and Rs represent a hydrogen atom or an electron withdrawing group; and each of Rp and Rq independently represents a hydrogen atom, a halogen atom, a C1-20 alkyl group, a C1-20 alkoxy group, an aryl group, or a heteroaryl group.

Singlet oxygen generation by novel NIR BODIPY dyes

Five novel near-infrared BODIPY dyes were prepared for improved singlet oxygen generation using thiophene and bromine. Theoretical, optical, photostable, and singlet oxygen generation characteristics of these dyes were assessed. Predicted excitation energ

Bright, color-tunable fluorescent dyes in the Vis/NIR region: Establishment of new "tailor-made" multicolor fluorophores based on borondipyrromethene

A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.

FLUORESCENT COMPOUND AND LABELING AGENT COMPRISING THE SAME

A novel fluorescent compound having a high light fastness, high fluorescence quantum yield and sharp absorption spectrum, which emits fluorescence having a wavelength in long wavelength region, as well as its use as a labeling agent, is disclosed. In Form

Bright, color-tunable fluorescent dyes in the visible-near-infrared region

The newly synthesized Keio Fluors, which are based on boron-dipyrromethene (BDP), have excellent and useful optical properties: vivid colors and sharp emission in the visible-near-infrared region (583-738 nm), high quantum yields (Φ: 0.56-0.98), high exti