Technology Process of 3,5-dibromo-O,α-dimethyl-D-tyrosine
There total 1 articles about 3,5-dibromo-O,α-dimethyl-D-tyrosine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; bromine;
In
water;
at 5 ℃;
for 0.25h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid; hydrogen bromide / acetic acid / 17 h / 70 - 80 °C / Inert atmosphere
2.1: hydrogen bromide / water / 5 h / Reflux
2.2: 12 h / 3863.02 Torr
2.3: 10 h
3.1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / acetonitrile; tetrahydrofuran / 3 h / 0 - 20 °C
With
hydrogen bromide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; water; acetic acid; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: trifluoroacetic acid; hydrogen bromide / acetic acid / 17 h / 70 - 80 °C / Inert atmosphere
2.1: hydrogen bromide / water / 5 h / Reflux
2.2: 12 h / 3863.02 Torr
2.3: 10 h
3.1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / acetonitrile; tetrahydrofuran / 3 h / 0 - 20 °C
4.1: hydrogenchloride / ethanol
With
hydrogenchloride; hydrogen bromide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; ethanol; water; acetic acid; acetonitrile;
