4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

Base Information

Chemical Name:4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide
CAS No.:798549-83-4
Molecular Formula:C₂₇H₃₂N₄OS
Molecular Weight:460.643
Hs Code.:

Synonyms:4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

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Chemical Property of 4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

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Technology Process of 4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

There total 1 articles about 4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 798550-21-7
N,N-diethyl-4-[(2-nitrophenyl)(piperidin-4-ylidene)methyl]benzamide

: 7709-58-2
4-(chloromethyl)thiazole hydrochloride

: 798549-83-4
4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

Guidance literature:: N,N-diethyl-4-[(2-nitrophenyl)(piperidin-4-ylidene)methyl]benzamide; 4-(chloromethyl)thiazole hydrochloride; With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 18h;

With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 150 ℃; for 0.333333h; Microwave irradiation;

Reference yield: 19.0%

: 798549-83-4
4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide

: 76-05-1
trifluoroacetic acid

: 4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide, TFA salt

Guidance literature:: 4-{(2-aminophenyl)[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl}-N,N-diethylbenzamide; trifluoroacetic acid; In water; acetonitrile;

With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 150 ℃; for 0.333333h; Microwave irradiation;