7709-58-2Relevant academic research and scientific papers
N-substituted acylamino acid compounds, process for their production and their use
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, (2008/06/13)
The present invention provides an N-substituted acylamino acid compound of the formula: STR1 a process for their production and pharmaceutical uses, and intermediates useful for their production.
INDOLE CARBOXYLATE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS
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, (2008/06/13)
Compounds of the structure where A is straight or branched divalent alkylene or divalent cycloalkylene, R1 is selected from hydrogen; alkylthio; optionally substituted phenylthio; optionally substituted phenylalkylthio; optionally substituted 2-, 3-, and 4-pyridyl; optionally substituted 2-, and 3-thienylthio; and optionally substituted 2-thiazolythio, R2 is selected from -COOB; -COOalkyl; -COOalkyl(carbocyclic aryl); -CONR5R6 ; -COR6 ; and -OH, R3 is selected from phenylalkyl and heteroarylalkyl, and R4 is selected from optionally substituted alkoxy(carbocyclic aryl); optionally substituted carbocyclic aryloxy; optionally substituted heteroarylalkoxy; and optionally substituted heteroaryloxy are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states
Selective oxabicycloalkanes
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, (2008/06/13)
This invention relates to compounds, agriculturally suitable compositions thereof, and a method for controlling the growth of undesired vegetation in paddy rice with an oxabicycloalkane herbicide of the formula, JOCH2Q, wherein J is an oxabicycloalkane moiety; and, Q is an optionally substituted aromatic or heteroaromatic moiety.
