(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Base Information

Chemical Name:(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester
CAS No.:106162-91-8
Molecular Formula:C₃₂H₃₄N₂O₉S
Molecular Weight:622.696
Hs Code.:

(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Synonyms:(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Suppliers and Price of (2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

There total 7 articles about (2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 106162-90-7
(2S,3R,6R,7R)-7-Methoxy-3-methoxymethyl-3-methylsulfanyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

: 106162-91-8
(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 1.5h;
DOI:10.1021/jm00386a013

Reference yield:

: 68402-81-3
diphenylmethyl 7β-benzamido-7α-methoxy-3-<<(1-methyl-1H-yetrazol-5-yl)thio>methyl>-1-oxadethia-3-cephem-4-carboxylate

: 106162-91-8
(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 43 percent / acetic acid, magnesium / CH₂Cl₂ / 9 h / 20 °C

2: pyridine, phosphorus pentachloride / CH₂Cl₂ / 1.5 h / Ambient temperature

3: 53.8 percent / pyridine / CH₂Cl₂ / 1.) -20 deg C, 15 min, 2.) 0 deg C, 30 min

4: 100 percent / CH₂Cl₂; ethyl acetate / 2 h / 0 °C

5: 100 percent / calcium carbonate, silver perchlorate / 1.5 h / Ambient temperature

6: 100 percent / 80 percent m-chloroperbenzoic acid / CH₂Cl₂ / 1.5 h

With pyridine; phosphorus pentachloride; silver perchlorate; magnesium; acetic acid; 3-chloro-benzenecarboperoxoic acid; calcium carbonate; In dichloromethane; ethyl acetate;
DOI:10.1021/jm00386a013

Reference yield:

: 68314-03-4
(2R,6R,7R)-7-Amino-7-methoxy-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

: 106162-91-8
(2S,3R,6R,7R)-3-Methanesulfonyl-7-methoxy-3-methoxymethyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 53.8 percent / pyridine / CH₂Cl₂ / 1.) -20 deg C, 15 min, 2.) 0 deg C, 30 min

2: 100 percent / CH₂Cl₂; ethyl acetate / 2 h / 0 °C

3: 100 percent / calcium carbonate, silver perchlorate / 1.5 h / Ambient temperature

4: 100 percent / 80 percent m-chloroperbenzoic acid / CH₂Cl₂ / 1.5 h

With pyridine; silver perchlorate; 3-chloro-benzenecarboperoxoic acid; calcium carbonate; In dichloromethane; ethyl acetate;
DOI:10.1021/jm00386a013