3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone

Base Information

• Chemical Name: 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone
• CAS No.: 180792-90-9
• Molecular Formula: C₁₈H₁₄N₄OS
• Molecular Weight: 334.401
• Mol file: 180792-90-9.mol

Synonyms:3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone

Chemical Property of 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone

There total 4 articles about 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

orthoformic acid triethyl ester (122-51-0) + 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate (180793-00-4) → 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone (180792-90-9)

Guidance literature:

With acetic anhydride; In ethanol; for 3h; Heating;

DOI:10.1002/jccs.199900130

Reference yield:

3-Amino-4,6-dimethylthieno<2,3-b>pyridine-2-carbohydrazide (128918-28-5) → 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone (180792-90-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / glacial acetic acid / ethanol / 4 h / Heating

2: 87 percent / Ac₂O / 3 h / Heating

With acetic anhydride; acetic acid; In ethanol;

DOI:10.1002/jccs.200100172

Reference yield:

benzaldehyde (100-52-7) → 3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone (180792-90-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / glacial acetic acid / ethanol / 4 h / Heating

2: 87 percent / Ac₂O / 3 h / Heating

With acetic anhydride; acetic acid; In ethanol;

DOI:10.1002/jccs.200100172

upstream raw materials:

orthoformic acid triethyl ester

3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate

3-Amino-4,6-dimethylthieno<2,3-b>pyridine-2-carbohydrazide

benzaldehyde