3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate

Base Information

• Chemical Name: 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate
• CAS No.: 180793-00-4
• Molecular Formula: C₁₇H₁₆N₄OS
• Molecular Weight: 324.406
• Mol file: 180793-00-4.mol

Synonyms:3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate

Chemical Property of 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate

There total 6 articles about 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-Amino-4,6-dimethylthieno<2,3-b>pyridine-2-carbohydrazide (128918-28-5) + benzaldehyde (100-52-7) → 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate (180793-00-4)

Guidance literature:

With acetic acid; In ethanol; for 4h; Heating;

DOI:10.1002/jccs.200100172

Reference yield: 59.0%

Benzylidenemalononitrile (2700-22-3) + 3-Amino-4,6-dimethylthieno<2,3-b>pyridine-2-carbohydrazide (128918-28-5) → 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate (180793-00-4)

Guidance literature:

With piperidine; In ethanol; Heating;

DOI:10.1002/jccs.199900130

Reference yield:

4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile (54585-47-6) → 3-amino-2-carboxybenzylidenehydrazide-4,6-dimethylthieno[2,3-b]pyridine carboxylate (180793-00-4)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium / ethanol / 6 h / Reflux

2: hydrazine hydrate / ethanol / 6 h / Reflux

3: pyridine / ethanol / 2 h / Reflux

With pyridine; hydrazine hydrate; sodium; In ethanol;

DOI:10.1080/14756366.2018.1457657

upstream raw materials:

Benzylidenemalononitrile

3-Amino-4,6-dimethylthieno<2,3-b>pyridine-2-carbohydrazide

benzaldehyde

ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Downstream raw materials:

3-N-benzylidene-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]-4(3H)-pyrimidinone

2-Mercapto-7,9-dimethyl-3-{[1-phenyl-meth-(E)-ylidene]-amino}-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one