(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Base Information

Chemical Name:(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate
CAS No.:889129-00-4
Molecular Formula:C₂₇H₃₂O₇S
Molecular Weight:500.613
Hs Code.:

Synonyms:(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Suppliers and Price of (2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

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Technology Process of (2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

There total 3 articles about (2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 123-76-2
levulinic acid

: 141810-60-8
ethyl 3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside

: 889129-00-4
(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1002/ejoc.200500816

Reference yield:

: 100-39-0
benzyl bromide

: 889129-00-4
(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: di-n-butyltin oxide / methanol / 18 h / 65 °C

1.2: 51 percent / cesium(I) fluoride / dimethylformamide / 24 h / 20 °C

2.1: 76 percent / DCC; DMAP / CH₂Cl₂ / 18 h / 20 °C

With dmap; di(n-butyl)tin oxide; dicyclohexyl-carbodiimide; In methanol; dichloromethane;
DOI:10.1016/j.carres.2006.03.007

Reference yield:

: 20701-61-5,56119-28-9,131564-36-8,142924-31-0,151123-92-1,141899-53-8
ethyl 4,6-O-benzylidene-1-thio-β-D-glucopyranoside

: 889129-00-4
(2R,4aR,6S,7R,8S,8aR)-8-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: di-n-butyltin oxide / methanol / 18 h / 65 °C

1.2: 51 percent / cesium(I) fluoride / dimethylformamide / 24 h / 20 °C

2.1: 76 percent / DCC; DMAP / CH₂Cl₂ / 18 h / 20 °C

With dmap; di(n-butyl)tin oxide; dicyclohexyl-carbodiimide; In methanol; dichloromethane;
DOI:10.1016/j.carres.2006.03.007