Sulfadiazine Sodium

Base Information

• Chemical Name: Sulfadiazine Sodium
• CAS No.: 547-32-0
• Molecular Formula: C10H9N4NaO2S
• Molecular Weight: 273.271
• Hs Code.: 2935009090
• European Community (EC) Number: 208-919-0
• UNII: 84CS1P306F
• ChEMBL ID: CHEMBL1200351
• DSSTox Substance ID: DTXSID20203152
• NCI Thesaurus Code: C66566
• Nikkaji Number: J188.396H
• RXCUI: 220087
• Wikidata: Q27269521
• Mol file: 547-32-0.mol

Synonyms:Sodium sulfadiazine;SULFADIAZINE SODIUM;547-32-0;Sulfadiazin-natrium;Sulfadiazine sodium salt;Soludiazine;Suthogen;Sodium sulfapyrimidine;Sulfadiazina sodica;Soluble sulfadiazine;Sulfadiazine (sodium);Monosodium 2-sulfanilamidopyrimidine;2-Sulfanilamidopyrimidine sodium salt;EINECS 208-919-0;NSC 117870;UNII-84CS1P306F;N(sup 1)-2-Pyrimidinylsulfanilamide monosodium salt;84CS1P306F;Sulfadiazina sodica [INN-Spanish];Sulfadiazine sodique [INN-French];Sulfadiazinum natricum [INN-Latin];NSC117870;Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosodium salt;Sodium, (N(sup 1)-2-pyrimidinylsulfanilamido)-;NSC-117870;Sulfanilamide, N(sup 1)-2-pyrimidinyl-, monosodium salt;Sulfadiazine sodium [USP:INN];DTXSID20203152;Sulfanilamide, N(sup 1)-2-pyrimidinyl-, N(sup 1)-sodium deriv;Sulfanilamide, N1-2-pyrimidinyl-, monosodium salt;MFCD00067333;sodium;(4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide;4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt;Solfadiazina sodica;Sulfadiazine sodique;Sulfadiazinum natricum;Sulfadiazine sodium (USP:INN);4-amino-N-(pyrimidin-2-yl)benzenesulfonamide, sodium salt;Sulfadiazina sodica (INN-Spanish);Sulfadiazine sodique (INN-French);SULFADIAZINE SODIUM (MART.);SULFADIAZINE SODIUM [MART.];Sulfadiazinum natricum (INN-Latin);Solfadiazina sodica [DCIT];SULFADIAZINE SODIUM (USP MONOGRAPH);SULFADIAZINE SODIUM [USP MONOGRAPH];SPS Agar Supplement;N1-2-Pyrimidinylsulfanilamide monosodium salt;Sulfadiazine sodium (TN);Sulfadiazine sodium (USP);Sulfadiazine Sodium(SD-Na);CHEMBL1200351;HY-B0273A;DTXCID20125643;SULFADIAZINE SODIUM [INN];BCP12144;s4634;SULFADIAZINE SODIUM [WHO-DD];AKOS024430976;AKOS025310751;CCG-267179;SULFADIAZINE SODIUM [GREEN BOOK];SULFADIAZINE SODIUM [ORANGE BOOK];AS-11709;SY256852;CS-0014298;NS00043366;D05949;A830351;4-amino-N-pyrimidin-2-ylbenzenesulfonamide;Q-201760;Q27269521;Sodium ((4-aminophenyl)sulfonyl)(pyrimidin-2-yl)amide;Sulfadiazine sodium salt, analytical standard, >=98%;4-Amino-N-2-pyrimidinylbenzenesulfonamide sodium salt (1:1)

Chemical Property of Sulfadiazine Sodium

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Boiling Point: 512.6oC at 760 mmHg
• Flash Point: 263.8oC
• PSA: 97.56000
• Density: 1.496g/cm3
• LogP: 2.38040
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 272.03439100
• Heavy Atom Count: 18
• Complexity: 332

Purity/Quality:

99.7% ^*data from raw suppliers

Sulfadiazine Sodium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38-42/43
• Safety Statements: 22-26-36/37-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]
• Uses: Sulfadiazine Sodium Salt can be used as reactant/reagent in preparation and crystal structure of aminophenyl sulfonamide tetrahalides, hydrochloride and hydrobromide cocrystals with iodine. Sulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.

Technology Process of Sulfadiazine Sodium

There total 3 articles about Sulfadiazine Sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulfadiazine (68-35-9) → poly[{μ3-4-[(pyrimidin-2-ylazanidyl)sulfonyl]aniline}sodium(I)] (547-32-0)

Guidance literature:

With sodium hydroxide; In ethanol; water; Heating;

DOI:10.1107/S205322961800414X

Reference yield:

→ poly[{μ3-4-[(pyrimidin-2-ylazanidyl)sulfonyl]aniline}sodium(I)] (547-32-0)

Guidance literature:

Herstellung;

DOI:10.1021/ja01865a027

Reference yield:

→ sulfadiazine sodium (547-32-0)

Guidance literature:

upstream raw materials:

sulfadiazine

Downstream raw materials:

Cu(sulfadiazine)2(H₂O)2

Mn(sulfadiazine)2(H₂O)2

Pd(sulfadiazine)(CH₃OH)Cl

Pt(sulfadiazine)(H₂O)Cl