Cellobiose

Base Information

• Chemical Name: Cellobiose
• CAS No.: 9004-34-6
• Molecular Formula: (C6H10O5)n
• Molecular Weight: 324.28
• Hs Code.: 39129090
• European Community (EC) Number: 232-674-9,200-716-5,208-436-5,232-686-4,619-425-3
• NSC Number: 2559
• Wikipedia: Cellulose,Cellobiose,Maltose
• Wikidata: Q105019941
• NCI Thesaurus Code: C68478,C68491
• RXCUI: 1311261,2221
• Mol file: 9004-34-6.mol

Synonyms:cellobiose;maltose;Epimaltose, Min.;D-(+)-Cellobiose;Cellobiose, .beta.-;4-BETA-GALACTOBIOSE;D-Cellobiose;D-Maltose;Lactose, alpha-;NSC2559;69-79-4;Lactose, .beta.-;.beta.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-;13360-52-6;528-50-7;4-O-beta-D-Glucopyranosyl-D-glucose;4-O-B-D-MANNOPYRANOSYL-D-GLUCOPYRANOSIDE;cellulose;Cextromaltose;Maltobiose;Maltodiose;Mannobiose;Cellose;Finetose;Sunmalt;4-o-(a-d-galactopyranosyl)-d-glucopyranose;Malt sugar;Finetose F;9004-34-6;.beta.-D-Glucopyranose, 4-O-.beta.-D-glucopyranosyl-;Sunmalt S;Advanctose 100;.beta.-D-Lactose;Maltose [JAN];D-(+)-Maltose;beta-1,4-Mannobiose;.EC.-Cellobiose;D-Glucose, 4-O-.beta.-D-glucopyranosyl-;56907-30-3;80446-85-1;9005-84-9;cellulose microcrystalline;4-(alpha-D-Glucosido)-D-glucose;D-Glucosyl-beta-(1-4)-D-glucose;EINECS 200-716-5;4-O-alpha-D-Glucopyranosyl-D-glucose;D-Glucose, 4-O-?-D-glucopyranosyl-;4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranose;alpha-D-Lactose;alpha-Lactose;4-beta-D-glucopyranosyl-D-glucopyranose;BRN 0093798;.beta.-Cellobiose;27452-49-9;29276-55-9;AI3-09089;4-(alpha-D-Glucopyranosido)-alpha-glucopyranose;.beta.-Maltose monohydrate;D04RYY;D0K8XC;EC-D-Glucopyranose, 4-O-EC-D-glucopyranosyl-;SCHEMBL684118;SCHEMBL20276017;SCHEMBL21511124;SCHEMBL23708014;SCHEMBL24202679;GUBGYTABKSRVRQ-UHFFFAOYSA-N;NSC-2559;AKOS015896855;FT-0619322;FT-0619323;FT-0622905;FT-0624351;FT-0624878;FT-0625411;FT-0625540;FT-0625541;FT-0670942;FT-0689214;FT-0697032;4-O- beta -D-Mannopyranosyl-D-glucopyranoside;EN300-719072;4-O-.beta.-D-Galactopyranosyl-.beta.-D-glucopyranose;4E82838F-6188-429E-B7BF-E9E27F9F648E;2-(hydroxymethyl)-6-{[4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol

Chemical Property of Cellobiose

Chemical Property:

• Appearance/Colour: White crystal powder
• Vapor Pressure: 1.08E-20mmHg at 25°C
• Melting Point: 260-270oC
• Refractive Index: n20/D 1.504
• Boiling Point: 667.9°C at 760 mmHg
• Flash Point: 164oC
• PSA: 0.00000
• Density: 1.27-1.60 g/cm3 (20oC)
• LogP: 0.00000
• Storage Temp.: room temp
• Solubility.: insoluble
• Water Solubility.: insoluble
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 342.11621151
• Heavy Atom Count: 23
• Complexity: 382

Purity/Quality:

98% ^*data from raw suppliers

Micro crystalline cellulose ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 37:
• Hazard Codes: Xi
• Statements: 37
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Polysaccharides,Biological Agents -> Disaccharides
• Canonical SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)O)CO)O)O)O)O
• Recent ClinicalTrials: Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis
• Uses: High purity cellulose powders for partition chromatography. ACCEL-101 is most widely used for direct compression tableting and wet granulation. ACCEL-102 has similar compression properties to ACCEL-101. However, it has larger particle size and therefore, may be of value in improving the flow if fine powders. ACCEL cellulose is a thickener and an emulsifier. It is obtained from plants. cellulose (microcrystalline) is used as an emulsifier in cosmetic creams. It is the chief constituent of plant fiber. Wood contains 50–70% cellulose; cotton and other textile fibers of plant origin contain 65–95%; rayon is prepared by dissolving natural cellulose and then precipitating it from solution, with some loss of crystallinity. Cellulose is made into cellophane film and is used to form fibers, resins, coatings and gums. Cellulose is a carbohydrate polymer made up of glucose units. It consists of fibrous particles and is used as a fiber source and bulking agent in low-calorie formulations. Microcrystalline Cellulose is a gum that is the nonfibrous form of cellulose, an alpha-cellulose. It is dispersible in water but not soluble, requiring considerable energy to disperse and hydrate. In this form it is used in dry applications such as tableting, capsules, and shredded cheese where it functions as a non-nutritive filler, binder, flow aid, and anticaking agent. By the addition of carboxymethylcellulose to the alpha-cellulose prior to drying, improved functional properties of hydration and dispersion are obtained. This product is designed for use in water dispersions, being insoluble in water but dispersing in water to form colloidal sols below 1% and white opaque gels above the 1% usage level. It is used as a heat shock stabilizer and bodying agent in frozen desserts, as an opacifier in low-fat dressings, as a foam stabilizer in whipped toppings, and as an emulsifier in dressings. Also termed cellulose gel.

Technology Process of Cellobiose

There total 8 articles about Cellobiose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,6-di-O-(4-methoxytrityl)cellulose → cellulose (9004-34-6)

Guidance literature:

With iron(III) chloride; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2009.01.144

Reference yield: 92.0%

β-D-glucopyranosyl-(1->4)-α-D-glucopyranosyl fluoride (103531-01-7) → cellulose (9004-34-6)

Guidance literature:

With Humicola insolens cellulase HiCel₇B E₁₉₇A mutant; In aq. phosphate buffer; at 40 ℃; for 24h; pH=7.8; Enzymatic reaction;

DOI:10.1021/acs.biomac.5b01453

Reference yield:

Cellulose acetate → cellulose (9004-34-6)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 168h;

DOI:10.1016/j.carbpol.2009.12.004

upstream raw materials:

D-Glucose

Cellobiose

β-D-glucopyranosyl-(1->4)-α-D-glucopyranosyl fluoride

Downstream raw materials:

furfural

5-hydroxymethyl-2-furfuraldehyde

acetic acid

mannitol

Refernces

• 1、 Baklagina,Khripunov,Tkachenko,Gladchenko,Lavrent'ev,Volkov,Nilova,Denisov,Sukhanova,Zanaveskina,Klechkovskaya,Feigin. "Structural parameters of cellulose produced by Acetobacter Xylinum and their variation in the course of drying of gel films". . p. 989 - 996. Retrieved 2003.
• 2、 Egusa, Shizuka,Kitaoka, Takuya,Goto, Masahiro,Wariishi, Hiroyuki. "Synthesis of cellulose in vitro by using a cellulase/surfactant complex in a nonaqueous medium". . p. 2063 - 2065. Retrieved 2007.
• 3、 Malm, Erik,Bulone, Vincent,Wickholm, Kristina,Larsson, Per Tomas,Iversen, Tommy. "The surface structure of well-ordered native cellulose fibrils in contact with water". . p. 97 - 100. Retrieved 2010.
• 4、 -. "Functionalised Chromatography Medium Comprising Polymer Nanofibres and Process of Preparation Thereof". Page/Page column 18-27; 29. . Retrieved 2019/10/20.
• 5、 -. "MULTISTAGE FRACTIONATION PROCESS FOR RECALCITRANT C5 OLIGOSACCHARIDES". . . Retrieved 2012/11/13.