(E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one

Base Information

• Chemical Name: (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one
• CAS No.: 134994-58-4
• Molecular Formula: C₂₃H₂₉NO₂
• Molecular Weight: 351.489
• Mol file: 134994-58-4.mol

Synonyms:(E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one

Chemical Property of (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one

There total 5 articles about (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.6%

(E)-1-(4-(6-bromohexyloxy)phenyl)-3-phenylprop-2-en-1-one (1262136-42-4) + dimethyl amine (124-40-3) → (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one (134994-58-4)

Guidance literature:

With potassium carbonate; sodium iodide; In acetone; for 8h; Reflux;

DOI:10.1016/j.bmc.2014.08.033

Reference yield:

(E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one (2657-25-2) → (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one (134994-58-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 °C

2: potassium carbonate; sodium iodide / acetone / 8 h / Reflux

With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.bmc.2014.08.033

Reference yield:

4-Hydroxyacetophenone (99-93-4) → (E)-1-(4-(6-(dimethylamino)hexyloxy)phenyl)-3-phenylprop-2-en-1-one (134994-58-4)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / ethanol; water / 24 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 80 °C

3: potassium carbonate; sodium iodide / acetone / 8 h / Reflux

With potassium carbonate; sodium iodide; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.bmc.2014.08.033

upstream raw materials:

(E)-1-(4-(6-bromohexyloxy)phenyl)-3-phenylprop-2-en-1-one

dimethyl amine

4-Hydroxyacetophenone

benzaldehyde