Indolizine-2-carbonitrile

Base Information

Chemical Name:Indolizine-2-carbonitrile
CAS No.:153274-67-0
Molecular Formula:C9H6 N2
Molecular Weight:142.16
Hs Code.:
European Community (EC) Number:865-340-1
DSSTox Substance ID:DTXSID80700930
Nikkaji Number:J2.041.575D
Wikidata:Q82632442
Mol file:153274-67-0.mol

Synonyms:INDOLIZINE-2-CARBONITRILE;153274-67-0;2-Indolizinecarbonitrile;2-cyanoindolizine;SCHEMBL1994209;DTXSID80700930;LOQCUYOSKCAMJF-UHFFFAOYSA-N;AKOS026729824;CS-0261396;EN300-78381;Z1203730717

Suppliers and Price of Indolizine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
indolizine-2-carbonitrile
250mg
$ 310.00

American Custom Chemicals Corporation
INDOLIZINE-2-CARBONITRILE 95.00%
5MG
$ 502.34

AK Scientific
Indolizine-2-carbonitrile
5g
$ 1269.00

AK Scientific
Indolizine-2-carbonitrile
1g
$ 503.00

Total 6 raw suppliers

Chemical Property of Indolizine-2-carbonitrile

Chemical Property:

PSA：28.20000
LogP:1.81098
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:142.053098200
Heavy Atom Count:11
Complexity:191

Purity/Quality:

99% ^*data from raw suppliers

indolizine-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=CC(=CN2C=C1)C#N

Technology Process of Indolizine-2-carbonitrile

There total 3 articles about Indolizine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 153274-57-8
(+/-)-2-[(hydroxy)(pyridin-2-yl)methyl]acrylonitrile

: 153274-67-0
indolizine-2-carbonitrile

Guidance literature:: In 2,2,2-trifluoroethanol; at 100 ℃; for 1h; Time; Solvent; Microwave irradiation;
DOI:10.5935/0103-5053.20130056

Reference yield: 32.0%

: 153274-62-5
3-acetoxy-2-methylene-3-(2-pyridyl)propiononitrile

: 153274-67-0
indolizine-2-carbonitrile

Guidance literature:: at 120 ℃; for 1h;

Reference yield:

: 1121-60-4
pyridine-2-carbaldehyde

: 153274-67-0
indolizine-2-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / DABCO / CHCl₃ / 72 h / Ambient temperature

2: 58 percent / 5 h / 100 °C

3: 32 percent / 1 h / 120 °C

With 1,4-diaza-bicyclo[2.2.2]octane; In chloroform;