C₂₅H₄₅NO₇SSi

Base Information

• Chemical Name: C₂₅H₄₅NO₇SSi
• CAS No.: 1301261-29-9
• Molecular Formula: C₂₅H₄₅NO₇SSi
• Molecular Weight: 531.786
• Mol file: 1301261-29-9.mol

Synonyms:C₂₅H₄₅NO₇SSi

Chemical Property of C₂₅H₄₅NO₇SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₄₅NO₇SSi

There total 8 articles about C₂₅H₄₅NO₇SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (S)-4-((R)-1-(benzyloxy)but-3-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate (1301261-31-3) → C25H45NO7SSi (1301261-29-9)

Guidance literature:

Multi-step reaction with 4 steps

1: dimethylsulfide borane complex / tetrahydrofuran / 2 h / 0 °C

2: triethylamine / dichloromethane / 2 h / 0 °C

3: cerium(III) chloride heptahydrate; oxalyl dichloride / acetonitrile / 2 h / 20 °C

4: 1H-imidazole / dichloromethane / 2 h

With 1H-imidazole; oxalyl dichloride; cerium(III) chloride heptahydrate; dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1055/s-0030-1258418

Reference yield:

C21H33NO5 (1301261-32-4) → C25H45NO7SSi (1301261-29-9)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 2 h / 0 °C

2: cerium(III) chloride heptahydrate; oxalyl dichloride / acetonitrile / 2 h / 20 °C

3: 1H-imidazole / dichloromethane / 2 h

With 1H-imidazole; oxalyl dichloride; cerium(III) chloride heptahydrate; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1055/s-0030-1258418

Reference yield:

(4S,1'R)-4-(1'-hydroxybut-3'-enyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester (132328-52-0) → C25H45NO7SSi (1301261-29-9)

Guidance literature:

Multi-step reaction with 5 steps

1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran / 24 h / 20 °C

2: dimethylsulfide borane complex / tetrahydrofuran / 2 h / 0 °C

3: triethylamine / dichloromethane / 2 h / 0 °C

4: cerium(III) chloride heptahydrate; oxalyl dichloride / acetonitrile / 2 h / 20 °C

5: 1H-imidazole / dichloromethane / 2 h

With 1H-imidazole; oxalyl dichloride; cerium(III) chloride heptahydrate; dimethylsulfide borane complex; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1055/s-0030-1258418

upstream raw materials:

tert-butyl (S)-4-((R)-1-(benzyloxy)but-3-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate

C₂₁H₃₃NO₅

C₂₂H₃₅NO₇S

C₂₀H₃₉NO₄Si

Downstream raw materials:

tert-butyl (2S,3R)-3-(benzyloxy)-2-((tert-butyldimethylsilyloxy)methyl)piperidine-1-carboxylate

(2R,3R)-3-Benzyloxy-2-formyl-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl (2S,3R)-3-(benzyloxy)-2-(hydroxymethyl)piperidine-1-carboxylate