Chemical Property of Butyltriphenylphosphonium bromide
Chemical Property:
- Appearance/Colour:white crystalline powder
- Melting Point:240-243 °C(lit.)
- PSA：13.59000
- LogP:1.78460
- Storage Temp.:Inert atmosphere,Room Temperature
- Sensitive.:Hygroscopic
- Solubility.:Chloroform, Methanol
- Water Solubility.:soluble
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:6
- Exact Mass:398.07990
- Heavy Atom Count:24
- Complexity:273
- Purity/Quality:
-
98%, *data from raw suppliers
n-ButyltriphenylphosphoniumBromide *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
21/22-36/37/38
- Safety Statements:
36/37-36/37/39-26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
-
Uses
suzuki reaction Reactant for:
Free radical 5-exo-dig cyclization
Intramolecular hydroacylalkoxylation
Wittig reactions for stereoselective synthesis of alkenes
Dimerization of α-olefins
Alkylidenation of hydrazides for synthesis of indoles
Tandem cyclization and 1,2-thiolate shift of nitrogen ylides n-Butyltriphenylphosphonium Bromide is used in the synthesis of inhibitors of tubulin polymerization thus expressing antimitotic and antitubulin properties. Also used in the synthesis of 3-phenylpropanoic acids as peroxisome proliferator-activated receptor dual agonists affecting the mitochondrial carnitine system.
