C₂₄H₂₉N₇OS

Base Information

• Chemical Name: C₂₄H₂₉N₇OS
• CAS No.: 1203604-72-1
• Molecular Formula: C₂₄H₂₉N₇OS
• Molecular Weight: 463.607
• Mol file: 1203604-72-1.mol

Synonyms:C₂₄H₂₉N₇OS

Chemical Property of C₂₄H₂₉N₇OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₉N₇OS

There total 6 articles about C₂₄H₂₉N₇OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

[5-(4-amino-2,6-dimethyl-phenyl)-[1,2,4]triazin-3-yl]-(5-methoxy-benzothiazol-2-ylmethyl)-amine (1203604-68-5) + (2-chloroethyl)dimethylamine hydrochloride (4584-46-7) → C24H29N7OS (1203604-72-1)

Guidance literature:

With sodium hydrogencarbonate; sodium iodide; In butan-1-ol; at 110 ℃; for 72h; Inert atmosphere;

DOI:10.1021/jm301499r

Reference yield:

5-methoxybenzothiazole-2-carboxaldehyde (854059-90-8) → C24H29N7OS (1203604-72-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium methylate; hydroxylamine hydrochloride / ethanol / 20 °C / Inert atmosphere

2.1: acetic acid; zinc / 3 h / 20 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 50 - 80 °C / Inert atmosphere

4.1: hydrogenchloride / ethyl acetate; water / 1 h / 0 °C / Inert atmosphere

5.1: sodium hydrogencarbonate; sodium iodide / butan-1-ol / 72 h / 110 °C / Inert atmosphere

With hydrogenchloride; hydroxylamine hydrochloride; sodium methylate; sodium hydrogencarbonate; acetic acid; N-ethyl-N,N-diisopropylamine; sodium iodide; zinc; In ethanol; water; ethyl acetate; acetonitrile; butan-1-ol;

DOI:10.1021/jm301499r

Reference yield:

5-methoxy-1,3-benzothiazole-2-carbaldehyde oxime (1203605-11-1) → C24H29N7OS (1203604-72-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid; zinc / 3 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 50 - 80 °C / Inert atmosphere

3.1: hydrogenchloride / ethyl acetate; water / 1 h / 0 °C / Inert atmosphere

4.1: sodium hydrogencarbonate; sodium iodide / butan-1-ol / 72 h / 110 °C / Inert atmosphere

With hydrogenchloride; sodium hydrogencarbonate; acetic acid; N-ethyl-N,N-diisopropylamine; sodium iodide; zinc; In water; ethyl acetate; acetonitrile; butan-1-ol;

DOI:10.1021/jm301499r

upstream raw materials:

5-methoxybenzothiazole-2-carboxaldehyde

5-methoxy-1,3-benzothiazole-2-carbaldehyde oxime

(4-{3-[(5-methoxybenzothiazol-2-ylmethyl)amino][1,2,4]triazin-5-yl}-3,5-dimethylphenyl)carbamic acid tert-butyl ester

[5-(4-amino-2,6-dimethyl-phenyl)-[1,2,4]triazin-3-yl]-(5-methoxy-benzothiazol-2-ylmethyl)-amine

Downstream raw materials:

C₂₃H₂₇N₇OS