Cholesterylsuccinyl-N-hydroxysuccinimide

Base Information

Chemical Name:Cholesterylsuccinyl-N-hydroxysuccinimide
CAS No.:88848-79-7
Molecular Formula:C35H53 N O6
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID301008529
Mol file:88848-79-7.mol

Synonyms:cholesterylsuccinyl-N-hydroxysuccinimide;CHS-N-HS

Suppliers and Price of Cholesterylsuccinyl-N-hydroxysuccinimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Cholesterylsuccinyl-N-hydroxysuccinimide

Chemical Property:

Vapor Pressure:3.36E-22mmHg at 25°C
Boiling Point:692.7°C at 760 mmHg
Flash Point:372.7°C
PSA：91.75000
Density:1.18g/cm³
LogP:6.87450
XLogP3:7.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:565.37672373
Heavy Atom Count:41
Complexity:1160

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)C5C(=O)N(C(=O)C56C(=O)CCC6=O)O)C)C
Isomeric SMILES:C[C@H](CCCC(C)C)[C@H]1CCC2[C@@]1(CCC3C2CC=C4[C@@]3(CCC(C4)C5C(=O)N(C(=O)C56C(=O)CCC6=O)O)C)C

Technology Process of Cholesterylsuccinyl-N-hydroxysuccinimide

There total 2 articles about Cholesterylsuccinyl-N-hydroxysuccinimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 1510-21-0
cholesteryl hemisuccinate

: 88848-79-7
cholesterol-NHS ester

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at -10 - 20 ℃; for 4h;
DOI:10.1021/jm00376a014

Reference yield:

: 57-88-5
cholesterol

: 88848-79-7
cholesterol-NHS ester

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 24 h / 20 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 24 h / 0 °C / Inert atmosphere

With dmap; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane;

Reference yield: 10.0%

: 88848-79-7
cholesterol-NHS ester

: 91202-76-5
N-methyl>glycine hydrochloride salt

: 91202-79-8
N-methyl>-N^α-<4-(5-cholesten-5β-yloxy)succinyl>glycinamide

: 91208-73-0
C₄₉H₈₂N₂O₁₇

Guidance literature:: With N-ethylmorpholine;; In N,N-dimethyl acetamide; N,N-dimethyl-formamide; for 3.5h; Ambient temperature;
DOI:10.1021/jm00376a014