ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside

Base Information

• Chemical Name: ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside
• CAS No.: 1021496-29-6
• Molecular Formula: C₂₂H₂₉NO₃S
• Molecular Weight: 387.543
• Mol file: 1021496-29-6.mol

Synonyms:ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside

Chemical Property of ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside

There total 1 articles about ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl 2,4-di-O-benzyl-6-deoxy-1-thio-β-D-xylo-hexopyranosid-3-ulose (E)-oxime (1021496-28-5) → ethyl 3-amino-2,4-di-O-benzyl-3,6-dideoxy-1-thio-β-D-gulopyranoside (1021496-31-0) + ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside (1021496-29-6)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; toluene; at 0 ℃; for 5h;

DOI:10.1016/j.tet.2008.01.093

Reference yield: 82.0%

ethyl 3-amino-2,4-di-O-benzyl-3-deoxy-1-thio-β-D-fucopyranoside (1021496-29-6) + 2,2,2-Trichloroethyl chloroformate (17341-93-4) → ethyl 2,4-di-O-benzyl-3-deoxy-1-thio-3-(2,2,2-trichloroethoxycarbonylamino)-β-D-fucopyranoside (1021496-22-9)

Guidance literature:

With pyridine; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2008.01.093

upstream raw materials:

ethyl 2,4-di-O-benzyl-6-deoxy-1-thio-β-D-xylo-hexopyranosid-3-ulose (E)-oxime

Downstream raw materials:

ethyl 2,4-di-O-benzyl-3-deoxy-1-thio-3-(2,2,2-trichloroethoxycarbonylamino)-β-D-fucopyranoside