4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide

Base Information

• Chemical Name: 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide
• CAS No.: 86843-81-4
• Molecular Formula: C₁₉H₁₂Cl₂N₂O₂
• Molecular Weight: 371.222
• Mol file: 86843-81-4.mol

Synonyms:4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide

Chemical Property of 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide

There total 1 articles about 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-aminopyridine (504-29-0) + 4-chloro-benzoyl chloride (122-01-0) → 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide (86843-81-4)

Guidance literature:

Schotten-Baumann;

Reference yield: 89.0%

4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide (86843-81-4) → 4-chloro-N-(pyridine-2-yl)benzamide (14547-82-1)

Guidance literature:

With sodium carbonate; In ethanol; water; for 1h; Heating; Schotten-Baumann;

Reference yield:

4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide (86843-81-4) → 5-(4-chloro-phenyl)-1-[2]pyridyl-1H-tetrazole (86843-88-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / sodium carbonate / ethanol; H₂O / 1 h / Heating; Schotten-Baumann

2: PCl₅ / 1 h / 100 °C

3: sodium azide, sodium acetate / H₂O; acetone / 12 h

With sodium azide; phosphorus pentachloride; sodium acetate; sodium carbonate; In ethanol; water; acetone;

upstream raw materials:

2-aminopyridine

4-chloro-benzoyl chloride

Downstream raw materials:

4-chloro-N-(pyridine-2-yl)benzamide

5-(4-chloro-phenyl)-1-[2]pyridyl-1H-tetrazole

2-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine