14547-82-1

Basic information

• Product Name: BENZAMIDE, 4-CHLORO-N-2-PYRIDINYL-
• Synonyms: 4-CHLORO-N-2-PYRIDINYL-BENZAMIDE;BENZAMIDE, 4-CHLORO-N-2-PYRIDINYL-
• CAS NO: 14547-82-1
• Molecular Formula: C₁₂H₉ClN₂O
• Molecular Weight: 232.669
• Mol File: 14547-82-1.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 307.5°C at 760 mmHg
• Flash Point: 139.8°C
• Appearance: /
• Density: 1.341g/cm³
• Vapor Pressure: 0.000724mmHg at 25°C
• Refractive Index: 1.657
• CAS DataBase Reference: BENZAMIDE, 4-CHLORO-N-2-PYRIDINYL-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZAMIDE, 4-CHLORO-N-2-PYRIDINYL-(14547-82-1)
• EPA Substance Registry System: BENZAMIDE, 4-CHLORO-N-2-PYRIDINYL-(14547-82-1)

Safety Data

• Hazardous Substances Data: 14547-82-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H9ClN2O/c13-10-6-4-9(5-7-10)12(16)15-11-3-1-2-8-14-11/h1-8H,(H,14,15,16)

Upstream product

• 504-29-0 2-aminopyridine 
• 122-01-0 4-chloro-benzoyl chloride 
• 86843-81-4 4-Chloro-N-[1-(4-chloro-benzoyl)-1H-pyridin-(2E)-ylidene]-benzamide 
• 62-53-3 aniline 
• 70-11-1 α-bromoacetophenone 
• 99-91-2 para-chloroacetophenone 
• 38922-74-6 2-(4-chlorophenyl)imidazolo[1,2-a]pyridine 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 923748-45-2 N-(pyridin-2-yl)monomethyl terephthalate monoamide 
• 74037-48-2 N-(1,2-diphenylethyl)pyridin-2-amine 
• 96354-74-4 N-(diphenylmethyl)pyridin-2-amine 
• 5223-01-8 2-phenyl-N-(pyridin-2-yl)acetamide 
• 4589-12-2 N-(pyrid-2-yl)benzamide 
• 4981-63-9 4-n-butanoylchlorobenzene 

Downstream Products

• 86843-88-1 5-(4-chloro-phenyl)-1-[2]pyridyl-1H-tetrazole 
• 1374639-95-8 N-[(Z)-(1H-1,2,3-benzotriazol-1-yl)(4-chlorophenyl)methylene]pyridin-2-amine 
• 1374639-83-4 (2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)(phenyl)methanone 
• 210035-02-2 (1H-imidazo[1,2-a]pyridin-3-yl)(phenyl)methanone 
• 86848-88-6 2-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

Copper(I)-catalysed aerobic oxidative selective cleavage of C[sbnd]C bond with DMAP: Facile access to N-substituted benzamides

A base/DMAP system for efficient oxidative cleavage of C(CO)–C(alkyl) bond to generate N-substituted benzamides has been developed in the presence of copper(I) chloride. The usage of inexpensive copper catalyst, broad substrate scope, mild conditions make

Singlet oxygen mediated dual C-C and C-N bond cleavage in visible light

A tandem cleavage of carbon-carbon and carbon-nitrogen bonds in imidazo[1,2-a]pyridines and imidazo[1,2-a]quinolines is reported in the presence of eosin Y and visible light. The ring opening occurs under ambient conditions through singlet oxygen insertio

Singlet oxygen mediated one pot synthesis of N-pyridinylamides via oxidative amidation of aryl alkyl ketones

An environmental friendly, efficient protocol has been realized for the synthesis of N-pyridinylamides via copper catalyzed oxidative amidation of aryl alkyl ketones with 2-aminopyridines. This one pot protocol involves chemo selective cleavage of C (O)–C bond in the presence of singlet oxygen. The reaction conditions are simple, tolerates wide range of substrates and the products were formed in good to excellent yields. This method offers a moderate improvement over the earlier successful attempts in generating N-pyridinylamides.