Technology Process of trifluoromethanesulfonic acid 1-methyl-cyclohexylmethyl ester
There total 4 articles about trifluoromethanesulfonic acid 1-methyl-cyclohexylmethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 75 percent / n-BuLi, diisopropylamine / hexane; tetrahydrofuran / 1.) -78 deg C, 2.) -78 - 0 deg C, 3.) room temperature, 8 h
2: 75 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature
3: 2,6-lutidine / petroleum ether / 1 h / 0 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride; n-butyllithium; diisopropylamine;
In
tetrahydrofuran; diethyl ether; hexane; Petroleum ether;
DOI:10.1021/ja00392a031
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 75 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature
2: 2,6-lutidine / petroleum ether / 1 h / 0 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride;
In
diethyl ether; Petroleum ether;
DOI:10.1021/ja00392a031
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 68 percent / 2N sulfuric acid / 8 h / Heating
2: 75 percent / n-BuLi, diisopropylamine / hexane; tetrahydrofuran / 1.) -78 deg C, 2.) -78 - 0 deg C, 3.) room temperature, 8 h
3: 75 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature
4: 2,6-lutidine / petroleum ether / 1 h / 0 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride; n-butyllithium; sulfuric acid; diisopropylamine;
In
tetrahydrofuran; diethyl ether; hexane; Petroleum ether;
DOI:10.1021/ja00392a031
