(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Base Information

Chemical Name:(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid
CAS No.:1017934-67-6
Molecular Formula:C₁₉H₁₇F₆NO₂
Molecular Weight:405.34
Hs Code.:

Synonyms:(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Suppliers and Price of (S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

There total 3 articles about (S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₁₈F₅NO₂

: 1017934-67-6
(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Guidance literature:: C₁₆H₁₈F₅NO₂; With zinc(II) tetrahydroborate; In diethyl ether; at -30 - 20 ℃;

With hydrogenchloride; water; In diethyl ether;

Reference yield:

: 850646-50-3
(S)-2-benzyloxycarbonylamino-4,4-difluoro-5-phenyl-pentanoic acid methyl ester

: 1017934-67-6
(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogen bromide / 2 h / 20 °C

2.1: potassium carbonate / methanol / 50 °C

2.2: -30 - 20 °C

With hydrogen bromide; potassium carbonate; In methanol;

Reference yield:

: 850646-48-9
(2S)-2-benzyloxycarbonylamino-4-oxo-5-phenylpentanoic acid methyl ester

: 1017934-67-6
(S)-4,4-difluoro-5-phenyl-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: diethylamino-sulfur trifluoride / 72 h / 20 °C

2.1: hydrogen bromide / 2 h / 20 °C

3.1: potassium carbonate / methanol / 50 °C

3.2: -30 - 20 °C

With diethylamino-sulfur trifluoride; hydrogen bromide; potassium carbonate; In methanol;