1-[2-(4-Fluorophenyl)ethyl]piperazine

Base Information

Chemical Name:1-[2-(4-Fluorophenyl)ethyl]piperazine
CAS No.:70931-33-8
Molecular Formula:C12H17 F N2
Molecular Weight:208.279
Hs Code.:2933599090
European Community (EC) Number:846-358-9
DSSTox Substance ID:DTXSID00460286
Nikkaji Number:J2.000.244A
Wikidata:Q72475909
Mol file:70931-33-8.mol

Synonyms:1-[2-(4-fluorophenyl)ethyl]piperazine;70931-33-8;1-(4-fluorophenethyl)piperazine;Piperazine,1-[2-(4-fluorophenyl)ethyl]-;SCHEMBL2549429;DTXSID00460286;LODHVDKKTUZVDK-UHFFFAOYSA-N;AMY17802;[2-(4-fluorophenyl)ethyl]piperazine;MFCD09839701;AKOS005063481;1-[2-(4-fluoro-phenyl)ethyl]piperazine;BS-51722;E78295;EN300-102598;J-503300;Z594273998

Suppliers and Price of 1-[2-(4-Fluorophenyl)ethyl]piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[2-(4-fluorophenyl)ethyl]piperazine
10mg
$ 45.00

American Custom Chemicals Corporation
1-[2-(4-FLUOROPHENYL)ETHYL]PIPERAZINE 95.00%
5MG
$ 504.31

AK Scientific
1-[2-(4-Fluorophenyl)ethyl]piperazine
10g
$ 2603.00

AK Scientific
1-[2-(4-Fluorophenyl)ethyl]piperazine
500mg
$ 532.00

AK Scientific
1-[2-(4-Fluorophenyl)ethyl]piperazine
250mg
$ 342.00

Total 18 raw suppliers

Chemical Property of 1-[2-(4-Fluorophenyl)ethyl]piperazine

Chemical Property:

Vapor Pressure:0.000994mmHg at 25°C
Boiling Point:302 ºC
Flash Point:137 ºC
PSA：15.27000
Density:1.062
LogP:1.54010
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:208.13757671
Heavy Atom Count:15
Complexity:173

Purity/Quality:

98%min ^*data from raw suppliers

1-[2-(4-fluorophenyl)ethyl]piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CCC2=CC=C(C=C2)F

Technology Process of 1-[2-(4-Fluorophenyl)ethyl]piperazine

There total 6 articles about 1-[2-(4-Fluorophenyl)ethyl]piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: N-benzyl-N'-[2-(4-fluorophenyl)ethyl]piperazine

: 70931-33-8
1-[2-(4-fluorophenyl)-ethyl]-piperazine

Guidance literature:: With hydrogen; triethylamine; palladium dihydroxide; In ethanol; at 40 ℃; for 7h; under 1500.15 - 3000.3 Torr;
DOI:10.1002/chem.200305327

Reference yield: 60.0%

: 70931-36-1
1-ethoxycarbonyl-4-<2-(4-fluorophenyl)ethyl>piperazine

: 70931-33-8
1-[2-(4-fluorophenyl)-ethyl]-piperazine

Guidance literature:: With potassium hydroxide; In ethanol; at 120 ℃; for 3h;
DOI:10.1135/cccc19803182

Reference yield:

: 405-99-2
para-fluorostyrene

: 70931-33-8
1-[2-(4-fluorophenyl)-ethyl]-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran; hexane / 0.17 h / 20 °C

1.2: 87 percent / tetrahydrofuran; hexane / 24 h / 20 °C

2.1: 95 percent / H₂; Et₃N / Pd(OH)2/C / ethanol / 7 h / 40 °C / 1500.15 - 3000.3 Torr

With hydrogen; triethylamine; palladium dihydroxide; In tetrahydrofuran; ethanol; hexane;
DOI:10.1002/chem.200305327