Technology Process of phenacyl ether derivative of antimycin A3
There total 6 articles about phenacyl ether derivative of antimycin A3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetonitrile;
at 20 ℃;
for 18h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: dibutyl-BOTf; triethylamine
2: lithium hydroxide; dihydrogen peroxide
3: dmap; hydrogen; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / Pd/O
4: dmap; diethylamine
5: tetrabutyl ammonium fluoride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
6: potassium carbonate / acetonitrile / 18 h / 20 °C
With
dmap; lithium hydroxide; dibutyl-BOTf; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diethylamine; triethylamine;
Pd/O;
In
acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dmap; hydrogen; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / Pd/O
2: dmap; diethylamine
3: tetrabutyl ammonium fluoride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
4: potassium carbonate / acetonitrile / 18 h / 20 °C
With
dmap; tetrabutyl ammonium fluoride; hydrogen; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diethylamine;
Pd/O;
In
acetonitrile;
