769-54-0 Usage
Description
3-Fluoro-4-nitropyridine-N-oxide, a chemical compound with the molecular formula C5H3FN2O3, is a yellow crystalline solid. It is recognized for its nitro functionality, which positions it as a significant building block in organic chemistry. 3-FLUORO-4-NITROPYRIDINE-N-OXIDE is utilized in the synthesis of pharmaceuticals and agrochemicals, playing a crucial role in the development of various chemical compounds.
Uses
Used in Pharmaceutical Synthesis:
3-Fluoro-4-nitropyridine-N-oxide is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of molecules with specific therapeutic properties, making it valuable in medicinal chemistry.
Used in Agrochemical Production:
In the agrochemical industry, 3-Fluoro-4-nitropyridine-N-oxide is employed as a precursor in the production of pesticides and other agrochemicals. Its incorporation aids in the design of compounds that can effectively control pests and diseases in agriculture, thereby enhancing crop protection.
Used as a Reagent in Organic Chemistry:
3-Fluoro-4-nitropyridine-N-oxide also serves as a reagent in organic chemistry, facilitating various chemical reactions. Its presence can influence the course of synthesis, leading to the formation of desired products in organic processes.
Safety Considerations:
Given its potentially hazardous nature, 3-Fluoro-4-nitropyridine-N-oxide should be handled with care in laboratory settings. Proper safety measures, including the use of personal protective equipment and adherence to laboratory safety protocols, are essential to minimize risks associated with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 769-54-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 769-54:
(5*7)+(4*6)+(3*9)+(2*5)+(1*4)=100
100 % 10 = 0
So 769-54-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H3FN2O3/c6-4-3-7(9)2-1-5(4)8(10)11/h1-3H
769-54-0Relevant articles and documents
PYRAZINE COMPOUND
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, (2019/07/11)
PROBLEM TO BE SOLVED: To provide a compound showing improved control activity on various pests or its salt. SOLUTION: The present invention provides a pyrazine compound having a 4-pyridyl group represented by formula (1) or its salt. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT
Synthesis of: Meta -substituted [18F]3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N -oxides
Brugarolas,Freifelder,Cheng,Dejesus
supporting information, p. 7150 - 7152 (2016/06/09)
Due to their electron-rich aromatic structure, nucleophilic (radio)fluorination of pyridines is challenging, especially at the meta position. In this paper, we describe the first example of direct fluorination of a pyridine N-oxide to produce a meta fluorinated pyridine. Specifically, fluorination of 3-bromo-4-nitropyridine N-oxide produced in several minutes 3-fluoro-4-nitropyridine N-oxide in moderate yield at room temperature. This intermediate compound was later converted to 3-fluoro-4-aminopyridine easily by catalytic hydrogenation. Furthermore, this approach was successfully applied for labeling with fluorine-18. The use of pyridine N-oxides for the preparation of fluoropyridines is unprecedented in the chemical literature and has the potential to offer a new way for the synthesis of these important structures in pharmaceuticals and radiopharmaceuticals.
Chemical compounds
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Page/Page column 42, (2008/06/13)
Compounds of formula (I): compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating CCR5 receptor activity in a warm blooded animal).
