(4r,5s)-5-Hydroxyhexan-4-olide

Base Information

Chemical Name:(4r,5s)-5-Hydroxyhexan-4-olide
CAS No.:54656-51-8
Molecular Formula:C₆H₁₀O₃
Molecular Weight:130.144
Hs Code.:
DSSTox Substance ID:DTXSID601225479
Nikkaji Number:J304.092E
Wikidata:Q75064030
Metabolomics Workbench ID:117558

Synonyms:(4r,5s)-5-hydroxyhexan-4-olide;SCHEMBL20045095;DTXSID601225479;(4R,5S)-5-Hydroxy-4-hexanolide;(5R)-Dihydro-5-[(1S)-1-hydroxyethyl]-2(3H)-furanone;54656-51-8

Suppliers and Price of (4r,5s)-5-Hydroxyhexan-4-olide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4r,5s)-5-Hydroxyhexan-4-olide

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:130.062994177
Heavy Atom Count:9
Complexity:122

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1CCC(=O)O1)O
Isomeric SMILES:C[C@@H]([C@H]1CCC(=O)O1)O

Technology Process of (4r,5s)-5-Hydroxyhexan-4-olide

There total 5 articles about (4r,5s)-5-Hydroxyhexan-4-olide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 124558-70-9
(S)-4-Ethylsulfanyl-5-((S)-1-hydroxy-ethyl)-5H-furan-2-one

: 27610-27-1,31641-90-4,54656-51-8,56452-73-4,58957-60-1,89195-92-6,105814-63-9,114420-35-8,114420-37-0,130609-14-2
(S)-5-((R)-1-Hydroxy-ethyl)-dihydro-furan-2-one

Guidance literature:: Ra-Ni W₂; In ethanol; for 3h; Ambient temperature;
DOI:10.1055/s-1989-27308

Reference yield:

: 6089-09-4
4-pentynoic acid

: 27610-27-1,31641-90-4,54656-51-8,56452-73-4,58957-60-1,89195-92-6,105814-63-9,114420-35-8,114420-37-0,130609-14-2
(S)-5-((R)-1-Hydroxy-ethyl)-dihydro-furan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: lithium amide / liquid ammonia

2: sodium, liquid ammonia

3: 1.) m-chloroperbenzoic acid; 2.) Amberlyst-15 / 1.) CH₂Cl₂

With lithium amide; amberlyst-15; ammonia; sodium; 3-chloro-benzenecarboperoxoic acid; In ammonia;
DOI:10.1039/c39870001513