4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride

Base Information

• Chemical Name: 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride
• CAS No.: 754232-76-3
• Molecular Formula: C₈F₈OS
• Molecular Weight: 296.141
• Mol file: 754232-76-3.mol

Synonyms:4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride

Chemical Property of 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride

There total 2 articles about 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pentafluorothiobenzoic acid S-trifluoromethyl ester (754232-75-2) → 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride (754232-76-3)

Guidance literature:

In acetonitrile; at 20 ℃;

DOI:10.1016/j.tetlet.2004.06.073

Reference yield:

pentafluorobenzoylchloride (2251-50-5) → 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride (754232-76-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 1 h / 20 °C

2: acetonitrile / 20 °C

In acetonitrile;

DOI:10.1016/j.tetlet.2004.06.073

Reference yield: 73.0%

4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride (754232-76-3) → 4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid

Guidance literature:

4-trifluoromethylthio-2,3,5,6-tetrafluorobenzoic acid fluoride; With triethylamine; In acetonitrile; at 20 ℃; for 0.5h;

With potassium hydroxide; In water; acetonitrile; at 20 ℃; for 0.5h;

In sulfuric acid; pH=4 - 5; Further stages.;

DOI:10.1016/j.tetlet.2004.06.073

upstream raw materials:

pentafluorothiobenzoic acid S-trifluoromethyl ester

pentafluorobenzoylchloride