(Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Base Information

• Chemical Name: (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole
• CAS No.: 428516-73-8
• Molecular Formula: C₂₂H₂₉NOSi
• Molecular Weight: 351.564

Synonyms:(Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Chemical Property of (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

There total 1 articles about (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1,3-bis(trimethylsilyl)propyne (21752-80-7) + 3a,6,6-trimethyl-2-phenyl-3a,4,5,6-tetrahydropyrrolo[1,2-b]isoxazol-3-carbaldehyde (355019-18-0) → (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole (428516-73-8) + (E)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Guidance literature:

With titanium(IV) isopropylate; n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1.75h;

DOI:10.1002/1522-2675(20011219)84:12<3822::AID-HLCA3822>3.0.CO;2-O

Reference yield: 99.0%

(Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole (428516-73-8) → (Z)-3-(but-1-en-3-enyl)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenylpyrrolo[1,2-b]isoxazole (428516-88-5)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 24h;

DOI:10.1002/1522-2675(20011219)84:12<3822::AID-HLCA3822>3.0.CO;2-O

Reference yield: 87.0%

(Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole (428516-73-8) → (E)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Guidance literature:

With iodine; Photolysis;

DOI:10.1002/1522-2675(20011219)84:12<3822::AID-HLCA3822>3.0.CO;2-O

upstream raw materials:

1,3-bis(trimethylsilyl)propyne

3a,6,6-trimethyl-2-phenyl-3a,4,5,6-tetrahydropyrrolo[1,2-b]isoxazol-3-carbaldehyde

Downstream raw materials:

(Z)-3-(but-1-en-3-enyl)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenylpyrrolo[1,2-b]isoxazole

3a,4,5,6-tetrahydro-3a,6,6-trimethyl-3-[4-(4-methylphenyl)but-1-en-3-ynyl]-2-phenylpyrrolo[1,2-b]isoxazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 428516-73-8 (Z)-3a,4,5,6-tetrahydro-3a,6,6-trimethyl-2-phenyl-3-[4-(trimethylsilyl)but-1-en-3-ynyl]pyrrolo[1,2-b]isoxazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send