methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Base Information

Chemical Name:methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate
CAS No.:1253197-74-8
Molecular Formula:C₂₆H₂₉NO₅S
Molecular Weight:467.586
Hs Code.:

Synonyms:methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Suppliers and Price of methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

There total 5 articles about methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 177259-98-2
2-[(3-(benzyloxy)phenyl)]ethan-1-ol

: 511286-68-3
methyl (R)-2-(p-tosylamino)propionate

: 1253197-74-8
methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 17h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b00897

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 1253197-74-8
methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 h / 20 °C / Inert atmosphere

2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 17 h / 0 - 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.jmedchem.5b00897

Reference yield:

: 100-39-0
benzyl bromide

: 1253197-74-8
methyl (R)-l-2-{N-[2-(3-benzyloxyphenyl)ethyl]-N-(4-tosyl)amino}propionate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / 0.67 h / 100 °C / 3000.3 Torr / Microwave irradiation

2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 17 h / 0 - 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; In tetrahydrofuran;
DOI:10.1021/acs.jmedchem.5b00897