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(R)-1-N-Boc-3-hydroxypyrrolidine

Base Information Edit
  • Chemical Name:(R)-1-N-Boc-3-hydroxypyrrolidine
  • CAS No.:109431-87-0
  • Molecular Formula:C9H17NO3
  • Molecular Weight:187.239
  • Hs Code.:29339900
  • European Community (EC) Number:629-335-6
  • DSSTox Substance ID:DTXSID40424908
  • Nikkaji Number:J593.631D
  • Wikidata:Q72450661
  • Mol file:109431-87-0.mol
(R)-1-N-Boc-3-hydroxypyrrolidine

Synonyms:109431-87-0;(R)-1-N-Boc-3-hydroxypyrrolidine;(R)-1-Boc-3-hydroxypyrrolidine;(R)-(-)-N-Boc-3-pyrrolidinol;tert-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate;(r)-n-(tert-butoxycarbonyl)-3-hydroxypyrrolidine;(r)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate;(R)-1-N-Boc-3-hydroxy-pyrrolidine;(R)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;(R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol;(R)-N-tert-Butoxycarbonyl-(-)-3-pyrrolidinol;1-PYRROLIDINECARBOXYLIC ACID, 3-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, (3R)-;MFCD01317838;(r)-n-boc-3-pyrrolidinol;(R)-3-Hydroxypyrrolidine-1-carboxylic acid tert-butyl ester;N-Boc-3-pyrrolidinol;(R)-N-boc-3-hydropyrrolidine;(R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;r-bochp;BOC-(R)-3-pyrrolidinol;N-tert-butoxycarbonyl-(R)--(-)-3-pyrrolidinol;(R)-1-Boc-3-pyrrolidinol;SCHEMBL14494;(r)-(-)-boc-3-pyrrolidinol;(r)-n-boc-3-hydroxy-pyrrolidine;1-Boc-(R)-3-Hydroxypyrrolidine;DTXSID40424908;TERT-BUTYL (R)-3-HYDROXYPYRROLIDINE-1-CARBOXYLATE;APCBTRDHCDOPNY-SSDOTTSWSA-N;(R)-3-hydroxy-N-Boc-pyrrolidine;N-Boc-(R)-(-)-3-pyrrolidinol;(3R)-N-BOC-3-Hydroxypyrrolidine;(R)-(+)-1-Boc-3-pyrrolidinol;(3R)-1-BOC-3-hydroxypyrrolidine;BCP15468;(r)-1-n-boc-3-hydroxy pyrrolidine;AC-139;AKOS005145919;AKOS015838269;(3r)-(-)-n-boc-3-hydroxypyrrolidine;1-BOC-3(R)-HYDROXYPYRROLIDINE;CS-W001294;PS-3869;N-BOC-(R)-3-HYDROXYPYRROLIDINE;(3R)-(-) -N-BOC-3-hydroxypyrrolidine;(R)-(-)-N-Boc-3-pyrrolidinol, 98%;BP-13370;(3R)-N-tert-butoxycarbonylpyrrolidin-3-ol;(r)-3-hydroxypyrrolidine, n-boc protected;(3R)-1-tert-butoxycarbonyl-3-pyrrolidinol;(3R)-N-tert-butyloxycarbonylpyrrolidin-3-ol;(R)-1-t-butoxycarbonyl-3-hydroxypyrrolidine;1-t-butoxycarbonyl-3-(R)-hydroxypyrrolidine;AM20070681;B3054;N-(Tert-butoxycarbonyl)-(R)-3-pyrrolidinol;(3R)-1-t-butoxycarbonyl-3-hydroxypyrrolidine;(R)-3-hydroxy-1-tert-butoxycarbonylpyrrolidine;B-4540;EN300-116612;N-tert-Butoxycarbonyl-(R)-(-)-3-pyrrolidinol;N-tert-butoxycarbonyl-(R)-3-hydroxypyrrolidine;t-butyl(3R)-3-hydroxypyrrolidine-1-carboxylate;(3R)-1-(t-butoxycarbonyl)-3-hydroxypyrrolidine;(3R)-1-tert-butoxycarbonyl-3-hydroxypyrrolidine;(3R)-N-(t-Butoxycarbonyl)-3-hydroxypyrrolidine;(3R)-N-tert-butoxycarbonyl-3-hydroxypyrrolidine;t-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate;tert-butyl(R)-3-hydroxypyrrolidine-1-carboxylate;(R)-tert-butyl 3-hydroxypyrrolidin-1-carboxylate;(R)-tert-butyl-3-hydroxypyrrolidin-1-carboxylate;A800671;tert-butyl 3-(R)-hydroxypyrrolidine-1-carboxylate;tert-butyl(3R)-3-hydroxypyrrolidine-1-carboxylate;tert-butyl(R)-3-hydroxy-pyrrolidine-1-carboxylate;(3R)-N-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;Q-102900;tert-butyl (3R)-3-oxidanylpyrrolidine-1-carboxylate;(R)-3-hydroxypyrrolidine-1-carboxylic acid t-butyl ester;1,1-Dimethylethyl (3R)-3-hydroxy-1-pyrrolidinecarboxylate;1,1-Dimethylethyl (3R)-3-hydroxypyrrolidine-1-carboxylate;3-(R)-Hydroxy-pyrrolidine-1-carboxylicacidtert-butylester;(3R)-3-hydroxy-1-pyrrolidinecarboxylic acid tert-butyl ester;(3R)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;(3R)-3-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester;(R)-3-Hydroxypyrrolidine-1 -carboxylic acid tert-butyl ester;(R)-(-)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of (R)-1-N-Boc-3-hydroxypyrrolidine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (R)-1-N-Boc-3-pyrrolidinol
  • 10 g
  • $ 155.00
  • TCI Chemical
  • (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
  • 5g
  • $ 127.00
  • TCI Chemical
  • (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
  • 1g
  • $ 27.00
  • SynQuest Laboratories
  • N-Boc-(R)-3-hydroxypyrrolidine
  • 1 g
  • $ 16.00
  • Sigma-Aldrich
  • (R)-(?)-N-Boc-3-pyrrolidinol 98%
  • 1g
  • $ 79.00
  • Sigma-Aldrich
  • (R)-(?)-N-Boc-3-pyrrolidinol 98%
  • 5g
  • $ 202.00
  • Matrix Scientific
  • (R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
  • 5g
  • $ 19.00
  • Matrix Scientific
  • (R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
  • 100g
  • $ 185.00
  • Matrix Scientific
  • (R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
  • 25g
  • $ 59.00
  • JR MediChem
  • (R)-(-)-N-Boc-3-pyrrolidinol 98%
  • 1kg
  • $ 518.00
Total 149 raw suppliers
Chemical Property of (R)-1-N-Boc-3-hydroxypyrrolidine Edit
Chemical Property:
  • Appearance/Colour:White to off-white powder 
  • Melting Point:62-65 °C(lit.) 
  • Refractive Index:-27 ° (C=1, MeOH) 
  • Boiling Point:273.3 °C at 760 mmHg 
  • PKA:14.74±0.20(Predicted) 
  • Flash Point:119.1 °C 
  • PSA:49.77000 
  • Density:1.142 g/cm3 
  • LogP:0.92600 
  • Storage Temp.:Store at 0-5°C 
  • Solubility.:soluble in Methanol 
  • XLogP3:0.6
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:2
  • Exact Mass:187.12084340
  • Heavy Atom Count:13
  • Complexity:198
Purity/Quality:

99.0%min *data from raw suppliers

(R)-1-N-Boc-3-pyrrolidinol *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38-53-50-50/53 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)O
  • Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@H](C1)O
  • Uses Used in synthesis of ligands for the nicotinic acetylcholine receptor.
Technology Process of (R)-1-N-Boc-3-hydroxypyrrolidine

There total 18 articles about (R)-1-N-Boc-3-hydroxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydrogencarbonate; In water; at 20 ℃; for 65h;
DOI:10.1039/P19930001421
Guidance literature:
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.12h;
Refernces Edit
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