(R)-1-N-Boc-3-hydroxypyrrolidine

Base Information Edit

Chemical Name:(R)-1-N-Boc-3-hydroxypyrrolidine
CAS No.:109431-87-0
Molecular Formula:C9H17NO3
Molecular Weight:187.239
Hs Code.:29339900
European Community (EC) Number:629-335-6
DSSTox Substance ID:DTXSID40424908
Nikkaji Number:J593.631D
Wikidata:Q72450661
Mol file:109431-87-0.mol

Synonyms:109431-87-0;(R)-1-N-Boc-3-hydroxypyrrolidine;(R)-1-Boc-3-hydroxypyrrolidine;(R)-(-)-N-Boc-3-pyrrolidinol;tert-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate;(r)-n-(tert-butoxycarbonyl)-3-hydroxypyrrolidine;(r)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate;(R)-1-N-Boc-3-hydroxy-pyrrolidine;(R)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;(R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol;(R)-N-tert-Butoxycarbonyl-(-)-3-pyrrolidinol;1-PYRROLIDINECARBOXYLIC ACID, 3-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, (3R)-;MFCD01317838;(r)-n-boc-3-pyrrolidinol;(R)-3-Hydroxypyrrolidine-1-carboxylic acid tert-butyl ester;N-Boc-3-pyrrolidinol;(R)-N-boc-3-hydropyrrolidine;(R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;r-bochp;BOC-(R)-3-pyrrolidinol;N-tert-butoxycarbonyl-(R)--(-)-3-pyrrolidinol;(R)-1-Boc-3-pyrrolidinol;SCHEMBL14494;(r)-(-)-boc-3-pyrrolidinol;(r)-n-boc-3-hydroxy-pyrrolidine;1-Boc-(R)-3-Hydroxypyrrolidine;DTXSID40424908;TERT-BUTYL (R)-3-HYDROXYPYRROLIDINE-1-CARBOXYLATE;APCBTRDHCDOPNY-SSDOTTSWSA-N;(R)-3-hydroxy-N-Boc-pyrrolidine;N-Boc-(R)-(-)-3-pyrrolidinol;(3R)-N-BOC-3-Hydroxypyrrolidine;(R)-(+)-1-Boc-3-pyrrolidinol;(3R)-1-BOC-3-hydroxypyrrolidine;BCP15468;(r)-1-n-boc-3-hydroxy pyrrolidine;AC-139;AKOS005145919;AKOS015838269;(3r)-(-)-n-boc-3-hydroxypyrrolidine;1-BOC-3(R)-HYDROXYPYRROLIDINE;CS-W001294;PS-3869;N-BOC-(R)-3-HYDROXYPYRROLIDINE;(3R)-(-) -N-BOC-3-hydroxypyrrolidine;(R)-(-)-N-Boc-3-pyrrolidinol, 98%;BP-13370;(3R)-N-tert-butoxycarbonylpyrrolidin-3-ol;(r)-3-hydroxypyrrolidine, n-boc protected;(3R)-1-tert-butoxycarbonyl-3-pyrrolidinol;(3R)-N-tert-butyloxycarbonylpyrrolidin-3-ol;(R)-1-t-butoxycarbonyl-3-hydroxypyrrolidine;1-t-butoxycarbonyl-3-(R)-hydroxypyrrolidine;AM20070681;B3054;N-(Tert-butoxycarbonyl)-(R)-3-pyrrolidinol;(3R)-1-t-butoxycarbonyl-3-hydroxypyrrolidine;(R)-3-hydroxy-1-tert-butoxycarbonylpyrrolidine;B-4540;EN300-116612;N-tert-Butoxycarbonyl-(R)-(-)-3-pyrrolidinol;N-tert-butoxycarbonyl-(R)-3-hydroxypyrrolidine;t-butyl(3R)-3-hydroxypyrrolidine-1-carboxylate;(3R)-1-(t-butoxycarbonyl)-3-hydroxypyrrolidine;(3R)-1-tert-butoxycarbonyl-3-hydroxypyrrolidine;(3R)-N-(t-Butoxycarbonyl)-3-hydroxypyrrolidine;(3R)-N-tert-butoxycarbonyl-3-hydroxypyrrolidine;t-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate;tert-butyl(R)-3-hydroxypyrrolidine-1-carboxylate;(R)-tert-butyl 3-hydroxypyrrolidin-1-carboxylate;(R)-tert-butyl-3-hydroxypyrrolidin-1-carboxylate;A800671;tert-butyl 3-(R)-hydroxypyrrolidine-1-carboxylate;tert-butyl(3R)-3-hydroxypyrrolidine-1-carboxylate;tert-butyl(R)-3-hydroxy-pyrrolidine-1-carboxylate;(3R)-N-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;Q-102900;tert-butyl (3R)-3-oxidanylpyrrolidine-1-carboxylate;(R)-3-hydroxypyrrolidine-1-carboxylic acid t-butyl ester;1,1-Dimethylethyl (3R)-3-hydroxy-1-pyrrolidinecarboxylate;1,1-Dimethylethyl (3R)-3-hydroxypyrrolidine-1-carboxylate;3-(R)-Hydroxy-pyrrolidine-1-carboxylicacidtert-butylester;(3R)-3-hydroxy-1-pyrrolidinecarboxylic acid tert-butyl ester;(3R)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;(3R)-3-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester;(R)-3-Hydroxypyrrolidine-1 -carboxylic acid tert-butyl ester;(R)-(-)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of (R)-1-N-Boc-3-hydroxypyrrolidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-1-N-Boc-3-pyrrolidinol
10 g
$ 155.00

TCI Chemical
(R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
5g
$ 127.00

TCI Chemical
(R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
1g
$ 27.00

SynQuest Laboratories
N-Boc-(R)-3-hydroxypyrrolidine
1 g
$ 16.00

Sigma-Aldrich
(R)-(?)-N-Boc-3-pyrrolidinol 98%
1g
$ 79.00

Sigma-Aldrich
(R)-(?)-N-Boc-3-pyrrolidinol 98%
5g
$ 202.00

Matrix Scientific
(R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
5g
$ 19.00

Matrix Scientific
(R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
100g
$ 185.00

Matrix Scientific
(R)-3-Hydroxy-pyrrolidine-1-carboxylic acidtert-butyl ester 95%
25g
$ 59.00

JR MediChem
(R)-(-)-N-Boc-3-pyrrolidinol 98%
1kg
$ 518.00

Total 152 raw suppliers

Chemical Property of (R)-1-N-Boc-3-hydroxypyrrolidine Edit

Chemical Property:

Appearance/Colour:White to off-white powder
Melting Point:62-65 °C(lit.)
Refractive Index:-27 ° (C=1, MeOH)
Boiling Point:273.3 °C at 760 mmHg
PKA:14.74±0.20(Predicted)
Flash Point:119.1 °C
PSA：49.77000
Density:1.142 g/cm³
LogP:0.92600
Storage Temp.:Store at 0-5°C
Solubility.:soluble in Methanol
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:187.12084340
Heavy Atom Count:13
Complexity:198

Purity/Quality:

99.0%min ^*data from raw suppliers

(R)-1-N-Boc-3-pyrrolidinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-53-50-50/53
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)O
Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@H](C1)O
Uses Used in synthesis of ligands for the nicotinic acetylcholine receptor.

Technology Process of (R)-1-N-Boc-3-hydroxypyrrolidine

There total 18 articles about (R)-1-N-Boc-3-hydroxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%