cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

Base Information

• Chemical Name: cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate
• CAS No.: 957185-37-4
• Molecular Formula: C₂₇H₃₇ClN₄O₇S₂
• Molecular Weight: 629.198

Synonyms:cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

Chemical Property of cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

There total 7 articles about cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

cyclopentyl N5-{[5-(1-bromo-2-oxopropyl)-2-chlorophenyl]sulfonyl}-N2-(tert-butoxycarbonyl)-L-ornithinate (957185-38-5) + acetylthiourea (591-08-2) → cyclopentyl N2-(tert-butoxycarbonyl)-N5-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate (957185-37-4)

Guidance literature:

In ethanol; at 70 ℃; for 1h;

Reference yield:

cyclopentyl N5-[(benzyloxy)carbonyl]-N2-(tert-butoxycarbonyl)-L-ornithinate (957185-06-7) → cyclopentyl N2-(tert-butoxycarbonyl)-N5-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate (957185-37-4)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogen / palladium dihydroxide / ethyl acetate / 2 h

2: sodium carbonate / 1,4-dioxane / 1.5 h / 20 °C

3: bromine / 1,4-dioxane / 1 h / 25 °C

4: ethanol / 1 h / 70 °C

With hydrogen; bromine; sodium carbonate; palladium dihydroxide; In 1,4-dioxane; ethanol; ethyl acetate;

Reference yield:

Boc-Orn(Z)-OH (2480-93-5) → cyclopentyl N2-(tert-butoxycarbonyl)-N5-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate (957185-37-4)

Guidance literature:

Multi-step reaction with 5 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C

2: hydrogen / palladium dihydroxide / ethyl acetate / 2 h

3: sodium carbonate / 1,4-dioxane / 1.5 h / 20 °C

4: bromine / 1,4-dioxane / 1 h / 25 °C

5: ethanol / 1 h / 70 °C

With dmap; hydrogen; bromine; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium dihydroxide; In 1,4-dioxane; ethanol; dichloromethane; ethyl acetate;

upstream raw materials:

cyclopentyl N₅-{[5-(1-bromo-2-oxopropyl)-2-chlorophenyl]sulfonyl}-N₂-(tert-butoxycarbonyl)-L-ornithinate

acetylthiourea

2-chloro-5-(2-oxopropyl)-benzenesulphonyl-chloride

cyclopentyl N₂-(tert-butoxycarbonyl)-L-ornithinate

Downstream raw materials:

cyclopentyl N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 957185-37-4 cyclopentyl N₂-(tert-butoxycarbonyl)-N₅-{[5-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-2-chlorophenyl]sulfonyl}-L-ornithinate

Send

Send

Metric Ton KG G Pound L ML

Send

Send