(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

Base Information

Chemical Name:(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester
CAS No.:927190-63-4
Molecular Formula:C₄₁H₃₉N₃O₅S
Molecular Weight:685.844
Hs Code.:

Synonyms:(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

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Chemical Property of (-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

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Technology Process of (-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

There total 1 articles about (-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 57092-52-1
N-Cbz-L-Phe-L-Phe-L-Phe-OH

: 108-98-5
thiophenol

: 927190-63-4
(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ja0658719

Reference yield: 85.0%

: 927190-63-4
(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

: 6783-05-7
trans-2-phenylvinylboronic acid

: (-)-2-(S)-benzyloxycarbonylamino-N-[1-(1-(S)-benzyl-2-oxo-4-phenyl-but-3-enylcarbamoyl)-2-phenyl-ethyl]-3-phenyl-(2S)-propionamide

Guidance literature:: With Cu(I) thiophenecarboxylate; triethyl phosphite; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/ja0658719

Reference yield: 80.0%

: 927190-63-4
(-)-N-benzyloxycarbonyl-L-phenylalanine-L-phenylalanine-L-phenylalanine thiophenyl ester

: 5720-07-0
4-methoxyphenylboronic acid

: (+)-2-(S)-benzyloxycarbonylamino-N-[1-[1-(S)-benzyl-2-(4-methoxy-phenyl)-2-oxo-ethylcarbamoyl]-2-phenyl-ethyl]-3-phenyl-(2S)-propionamide

Guidance literature:: With Cu(I) thiophenecarboxylate; triethyl phosphite; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/ja0658719