N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Base Information

Chemical Name:N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide
CAS No.:1258523-20-4
Molecular Formula:C₂₄H₃₆F₂N₂O₂SSi
Molecular Weight:482.71
Hs Code.:

Synonyms:N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Suppliers and Price of N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

There total 1 articles about N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1189175-68-5
N-{(3,4-difluorophenyl)[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]methylidene}-(R)-2-methyl-2-propanesulfinamide

: 75-16-1
methylmagnesium bromide

: 1258523-20-4
N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Guidance literature:: N-{(3,4-difluorophenyl)[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]methylidene}-(R)-2-methyl-2-propanesulfinamide; methylmagnesium bromide; In tetrahydrofuran; for 1h;

With water; sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield:

: 1258523-20-4
N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

: 1258523-26-0
N-{1-(3,4-difluorophenyl)-1-[5-(hydroxymethyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

Guidance literature:: N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

With water; sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield:

: 1258523-20-4
N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide

: {6-[1-amino-1-(3,4-difluorophenyl)ethyl]-3-pyridinyl}methanol

Guidance literature:: N-{1-(3,4-difluorophenyl)-1-[5-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-2-pyridinyl]ethyl}-(R)-2-methyl-2-propanesulfinamide; With hydrogenchloride; water; In methanol; at 0 - 20 ℃;

With sodium hydroxide; In methanol; water; pH=10; Cooling with ice;