ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate

Base Information

• Chemical Name: ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate
• CAS No.: 162713-44-2
• Molecular Formula: C₁₄H₁₄ClN₃O₃
• Molecular Weight: 307.736
• Mol file: 162713-44-2.mol

Synonyms:ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate

Chemical Property of ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate

There total 4 articles about ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

ethyl N-acetyl-N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate → ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate (162713-44-2)

Guidance literature:

With ammonium hydroxide; In ethanol; for 3h; Heating;

DOI:10.1002/ardp.19953280205

Reference yield: 65.0%

ethanol (64-17-5) + N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycine (162713-43-1,162811-07-6,162811-08-7) → ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate (162713-44-2)

Guidance literature:

With sulfuric acid; for 5h; Heating;

DOI:10.1002/ardp.19953280205

Reference yield:

2-thioxo-5-(4-chlorophenylmethylidene)-4-imidazolidinone (280137-25-9) → ethyl N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycinate (162713-44-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Na / ethanol

2: acetic acid / Heating

3: conc. H₂SO₄ / Heating

With sulfuric acid; sodium; In ethanol; acetic acid;

DOI:10.1016/S0022-2860(01)00584-1

upstream raw materials:

ethanol

N-<5-(4-chlorobenzylidene)-4-oxo-2-imidazolidinyl>glycine

2-thioxo-5-(4-chlorophenylmethylidene)-4-imidazolidinone

4-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1H-imidazol-5(4H)-one