3-chloro-3-pentafluorophenyldiazirine

Base Information

• Chemical Name: 3-chloro-3-pentafluorophenyldiazirine
• CAS No.: 1312886-29-5
• Molecular Formula: C₇ClF₅N₂
• Molecular Weight: 242.535
• Mol file: 1312886-29-5.mol

Synonyms:3-chloro-3-pentafluorophenyldiazirine

Chemical Property of 3-chloro-3-pentafluorophenyldiazirine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-chloro-3-pentafluorophenyldiazirine

There total 2 articles about 3-chloro-3-pentafluorophenyldiazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

pentafluorobenzamidine hydrochloride (1187927-16-7) → 3-chloro-3-pentafluorophenyldiazirine (1312886-29-5)

Guidance literature:

With sodium hypochlorite; lithium chloride; In water; dimethyl sulfoxide; pentane; at 20 ℃; for 2h;

DOI:10.1021/jp2039493

Reference yield:

Pentafluorobenzonitrile (773-82-0) → 3-chloro-3-pentafluorophenyldiazirine (1312886-29-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trimethylaluminum; ammonium chloride / toluene / 48 h / 80 °C / Inert atmosphere

1.2: 1 h

2.1: sodium hypochlorite; lithium chloride / water; dimethyl sulfoxide; pentane / 2 h / 20 °C

With sodium hypochlorite; trimethylaluminum; ammonium chloride; lithium chloride; In water; dimethyl sulfoxide; toluene; pentane; 1.1: Garigipati's reaction / 2.1: Graham oxidation;

DOI:10.1021/jp2039493

Reference yield: 78.0%

trans-2-Butene (624-64-6) + 3-chloro-3-pentafluorophenyldiazirine (1312886-29-5) → C11H8ClF5

Guidance literature:

In pentane; at 20 ℃; for 18h; Photolysis;

DOI:10.1021/ol2019532

upstream raw materials:

pentafluorobenzamidine hydrochloride

Pentafluorobenzonitrile

Downstream raw materials:

pentafluorophenylchlorocarbene

C₁₇H₁₆ClF₅