cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine

Base Information

• Chemical Name: cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine
• CAS No.: 7042-08-2
• Molecular Formula: C₂₁H₁₆N₂O₃
• Molecular Weight: 344.37
• Mol file: 7042-08-2.mol

Synonyms:cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine

Chemical Property of cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine

There total 2 articles about cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4-nitro-benzoyl chloride (122-04-3) + cis-2,3-diphenylaziridine (1605-06-7,855419-50-0) → cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine (7042-08-2)

Guidance literature:

With triethylamine; In diethyl ether; for 15h; Ambient temperature;

DOI:10.1016/0040-4020(96)00370-5

Reference yield:

cis-stilben (645-49-8) + 4-nitrobenzoyl azide (2733-41-7) → cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine (7042-08-2)

Guidance literature:

With dichlororuthenium(IV) meso-tetrakis(2,6-dichlorophenyl)porphyrin; In 1,2-dichloro-ethane; at 50 ℃; stereospecific reaction; Molecular sieve; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.202100668

Reference yield:

cis-1-(4-nitrobenzoyl)-2,3-diphenylaziridine (7042-08-2) + trimethylsilyl cyanide (7677-24-9) → (+)-anti-1-cyano-2-[N-(4-nitrobenzoyl)amino]-1,2-diphenylethane + (+)-syn-1-cyano-2-[N-(4-nitrobenzoyl)amino]-1,2-diphenylethane + (-)-anti-1-cyano-2-[N-(4-nitrobenzoyl)amino]-1,2-diphenylethane + (-)-syn-1-cyano-2-[N-(4-nitrobenzoyl)amino]-1,2-diphenylethane

Guidance literature:

With gadolinium(III) isopropoxide; 2.6-dimethylphenol; 1,5-anhydro-2,6-dideoxy-3-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol; trifluoroacetic acid; In various solvent(s); at 20 ℃; for 96h; Title compound not separated from byproducts;

DOI:10.1021/ja053486y

upstream raw materials:

4-nitro-benzoyl chloride

cis-2,3-diphenylaziridine

cis-stilben

4-nitrobenzoyl azide

Downstream raw materials:

2-(4-nitro-phenyl)-4r,5c-diphenyl-4,5-dihydro-oxazole

2-(4-nitro-phenyl)-4r,5t-diphenyl-4,5-dihydro-oxazole