4-deuterated benzonitrile

Base Information

• Chemical Name: 4-deuterated benzonitrile
• CAS No.: 13122-35-5
• Molecular Formula: C₇H₅N
• Molecular Weight: 104.115
• Mol file: 13122-35-5.mol

Synonyms:4-deuterated benzonitrile

Chemical Property of 4-deuterated benzonitrile

Chemical Property:

Purity/Quality:

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Technology Process of 4-deuterated benzonitrile

There total 12 articles about 4-deuterated benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-hydrazinobenzonitrile (17672-27-4) → 4-deuterated benzonitrile (13122-35-5)

Guidance literature:

With ammonium cerium (IV) nitrate; d⁽⁴⁾-methanol; at 20 ℃;

DOI:10.1055/s-2007-1072749

Reference yield: 82.0%

4-bromobenzenecarbonitrile (623-00-7) → 4-deuterated benzonitrile (13122-35-5)

Guidance literature:

With sodium formate; dimethyl sulfoxide; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; at 80 ℃; for 8h; Inert atmosphere;

Reference yield: 70.0%

1-(methylsulfonyl)-2-(4-cyanophenyl)diazene → 4-deuterated benzonitrile (13122-35-5)

Guidance literature:

With 1,1,1,2,3,3,3-heptadeuterio-2-propanol; In water; for 14h; Irradiation;

DOI:10.3390/molecules24112164

upstream raw materials:

4-Cyanochlorobenzene

4-bromobenzenecarbonitrile

4-iodobenzonitrile

2-acetyl-1-(4-cyanophenyl)hydrazine