C₃₃H₄₅N₇O₆

Base Information

• Chemical Name: C₃₃H₄₅N₇O₆
• CAS No.: 1373496-83-3
• Molecular Formula: C₃₃H₄₅N₇O₆
• Molecular Weight: 635.764
• Mol file: 1373496-83-3.mol

Synonyms:C₃₃H₄₅N₇O₆

Chemical Property of C₃₃H₄₅N₇O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₄₅N₇O₆

There total 10 articles about C₃₃H₄₅N₇O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C16H20N2O3 (1373496-77-5) + C17H25N5O3 (1373496-78-6) → C33H45N7O6 (1373496-83-3)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; water; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jo300063u

Reference yield:

2-amino-phenol (95-55-6) → C33H45N7O6 (1373496-83-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: hydrogenchloride; sodium nitrite / water / 0.08 h / -5 - -3 °C / Inert atmosphere

1.2: Inert atmosphere

1.3: 2 h / 0 °C / Inert atmosphere

2.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere

3.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere

3.2: pH 4

4.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

4.2: 12 h / 20 °C / Inert atmosphere

5.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; water / 12 h / 20 °C / Inert atmosphere

With hydrogenchloride; copper(ll) sulfate pentahydrate; lithium hydroxide monohydrate; potassium carbonate; sodium L-ascorbate; trifluoroacetic acid; potassium iodide; sodium nitrite; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jo300063u

Reference yield:

ethyl (2-((trimethylsilyl)ethynyl)phenoxy)acetate (1373496-66-2) → C33H45N7O6 (1373496-83-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere

2.2: pH 4

3.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C

3.2: 12 h / 20 °C / Inert atmosphere

4.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; water / 12 h / 20 °C / Inert atmosphere

With copper(ll) sulfate pentahydrate; lithium hydroxide monohydrate; tetrabutyl ammonium fluoride; sodium L-ascorbate; trifluoroacetic acid; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/jo300063u

upstream raw materials:

C₁₀H₈O₃

tert-butyl (2-(butylamino)-2-oxoethyl)carbamate

C₈H₇N₃O₃

C₁₆H₂₀N₂O₃