1,2-diphenyl-trans-4,5-dibromocyclohexene

Base Information

• Chemical Name: 1,2-diphenyl-trans-4,5-dibromocyclohexene
• CAS No.: 102367-83-9
• Molecular Formula: C₁₈H₁₆Br₂
• Molecular Weight: 392.133
• Mol file: 102367-83-9.mol

Synonyms:1,2-diphenyl-trans-4,5-dibromocyclohexene

Chemical Property of 1,2-diphenyl-trans-4,5-dibromocyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-diphenyl-trans-4,5-dibromocyclohexene

There total 1 articles about 1,2-diphenyl-trans-4,5-dibromocyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-diphenyl-1,4-cyclohexadiene (17351-29-0) → 1,2-diphenyl-trans-4,5-dibromocyclohexene (102367-83-9)

Guidance literature:

With bromine; In dichloromethane; chloroform; at -78 - 20 ℃;

DOI:10.1021/jo00364a031

Reference yield: 52.0%

1,2-diphenyl-trans-4,5-dibromocyclohexene (102367-83-9) → 1,6-diphenyl-trans-3,4-dibromo-7-oxabicyclo<4.1.0>heptane (102342-19-8)

Guidance literature:

With 3,5-dinitrobenzoic acid; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jo00364a031

Reference yield:

1,2-diphenyl-trans-4,5-dibromocyclohexene (102367-83-9) → (1,1';3',1''-terphenyl)-2'-ol (2432-11-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 52 percent / 3,5-dinitrobenzoic acid (3,5-DNPBA) / CH₂Cl₂ / 2 h / Ambient temperature

2: 72 percent / 1,5-diazabicyclo<4.3.0>non-5-ene (DBN) / tetrahydrofuran / 4.5 h / 0 - 20 °C

3: 100 percent / trifluoroacetic acid (TFA) / CDCl₃ / 0.25 h / Ambient temperature; other solvents, var. pH, var. reaction times

With 3,5-dinitrobenzoic acid; DBN; trifluoroacetic acid; In tetrahydrofuran; chloroform-d1; dichloromethane;

DOI:10.1021/jo00364a031

upstream raw materials:

1,2-diphenyl-1,4-cyclohexadiene

Downstream raw materials:

1,6-diphenyl-trans-3,4-dibromo-7-oxabicyclo<4.1.0>heptane

(1,1';3',1''-terphenyl)-2'-ol

2,7-diphenyloxepin