O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose

Base Information

• Chemical Name: O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose
• CAS No.: 868992-17-0
• Molecular Formula: C₃₀H₃₆O₁₁
• Molecular Weight: 572.609
• Mol file: 868992-17-0.mol

Synonyms:O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose

Chemical Property of O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose

There total 1 articles about O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

3-[4-(benzyloxy)phenyl]propan-1-ol (61440-45-7) + 2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate (74808-10-9,86520-63-0,87119-53-7,92052-29-4,121238-27-5,142831-80-9,127061-80-7) → O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose (868992-17-0)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1016/j.tet.2005.08.018

Reference yield: 99.0%

O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose (868992-17-0) → O-[3-(4-hydroxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galactopyranose (868992-03-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 2h; under 760 Torr;

DOI:10.1016/j.tet.2005.08.018

Reference yield:

O-[3-(4-phenylmethoxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galacto-pyranose (868992-17-0) → C42H52N2O14

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / hydrogen / Pd/C / ethanol / 2 h / 20 °C / 760 Torr

2: 55 percent / cesium carbonate / acetonitrile / 18 h / 20 °C

3: sodium methoxide; methanol / 15 h / 20 °C

With methanol; hydrogen; sodium methylate; caesium carbonate; palladium on activated charcoal; In ethanol; acetonitrile;

DOI:10.1016/j.tet.2005.08.018

upstream raw materials:

3-[4-(benzyloxy)phenyl]propan-1-ol

2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate

Downstream raw materials:

O-[3-(4-hydroxyphenyl)-1-propyl]-(2,3,4,6-O-tetraacetyl)-β-D-galactopyranose

acetic acid 3,5-diacetoxy-2-acetoxymethyl-6-{3-[4-(6'-{4-[3-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-propyl]-phenoxymethyl}-[2,2']bipyridinyl-6-ylmethoxy)-phenyl]-propoxy}-tetrahydro-pyran-4-yl ester

acetic acid 3,5-diacetoxy-2-acetoxymethyl-6-[3-(4-{3-[6'-(3-{4-[3-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-propyl]-phenoxymethyl}-phenyl)-[2,2']bipyridinyl-6-yl]-benzyloxy}-phenyl)-propoxy]-tetrahydro-pyran-4-yl ester