C₂₇H₂₂BNO₂

Base Information

• Chemical Name: C₂₇H₂₂BNO₂
• CAS No.: 1357066-50-2
• Molecular Formula: C₂₇H₂₂BNO₂
• Molecular Weight: 403.288
• Mol file: 1357066-50-2.mol

Synonyms:C₂₇H₂₂BNO₂

Chemical Property of C₂₇H₂₂BNO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₂₂BNO₂

There total 6 articles about C₂₇H₂₂BNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Triisopropyl borate (5419-55-6) + 10-(4-Bromophenyl)-12,12-dimethyl-10,12dihydro-10-azaindeno[2,1-b]-fluorene (1361126-22-8) → C27H22BNO2 (1357066-50-2)

Guidance literature:

10-(4-Bromophenyl)-12,12-dimethyl-10,12dihydro-10-azaindeno[2,1-b]-fluorene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h;

Reference yield:

2-bromo-9,9-dimethyl-9H-fluorene (28320-31-2) → C27H22BNO2 (1357066-50-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: palladium diacetate; sodium t-butanolate; tri-tert-butyl phosphine / toluene / 12 h / 120 °C

2.1: di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate / N,N-dimethyl acetamide / 12 h / 200 °C

3.1: copper(l) iodide; potassium phosphate; ethylenediamine / toluene / 12 h / 140 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

4.2: 12 h / -78 - 20 °C

With potassium phosphate; copper(l) iodide; n-butyllithium; tri-tert-butyl phosphine; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate; ethylenediamine; sodium t-butanolate; In tetrahydrofuran; hexane; N,N-dimethyl acetamide; toluene;

Reference yield:

o-chloroaniline (95-51-2) → C27H22BNO2 (1357066-50-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: palladium diacetate; sodium t-butanolate; tri-tert-butyl phosphine / toluene / 12 h / 120 °C

2.1: di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate / N,N-dimethyl acetamide / 12 h / 200 °C

3.1: copper(l) iodide; potassium phosphate; ethylenediamine / toluene / 12 h / 140 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

4.2: 12 h / -78 - 20 °C

With potassium phosphate; copper(l) iodide; n-butyllithium; tri-tert-butyl phosphine; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate; ethylenediamine; sodium t-butanolate; In tetrahydrofuran; hexane; N,N-dimethyl acetamide; toluene;

upstream raw materials:

Triisopropyl borate

10-(4-Bromophenyl)-12,12-dimethyl-10,12dihydro-10-azaindeno[2,1-b]-fluorene

2-bromo-9,9-dimethyl-9H-fluorene

o-chloroaniline

Downstream raw materials:

5-(4-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-7,7-dimethyl-5,7-dihydroindeno[2,1-b]carbazole

C₄₇H₃₃N₃