Multi-step reaction with 8 steps
1: 24 percent / charcoal, FeCl3*6H2O, N2H4*H2O / ethanol / 4 h / Heating; standing 2 weeks
2: 1) HCl, NaNO2, 2) potassium ethyl xanthate, Na2CO3 / 1) H2O, 0 to 2 deg C, 30 min, 2) 40 deg C, 30 min
3: 86 percent / K2CO3, Cu / dimethylformamide / 5 h / 140 °C
4: 82 percent / SOCl2 / pyridine / 6 h / Heating
5: 85 percent / 5 h / Heating
6: 88 percent / NaBH4, BF3*O(C2H5)2 / tetrahydrofuran / r.t., 5 h, reflux, 2 h
7: HCl / 0.5 h / 60 - 70 °C
8: 30.5 g / NaI / acetone / 20 h / Heating; standing overnight
With
hydrogenchloride; sodium tetrahydroborate; thionyl chloride; boron trifluoride diethyl etherate; potassium ethyl xanthogenate; iron(III) chloride; copper; sodium carbonate; potassium carbonate; pyrographite; hydrazine hydrate; sodium iodide; sodium nitrite;
In
tetrahydrofuran; pyridine; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1135/cccc19850519