2-chloro-N-methylpyridin-3-amine

Base Information

Chemical Name:2-chloro-N-methylpyridin-3-amine
CAS No.:40932-43-2
Molecular Formula:C6H7ClN2
Molecular Weight:142.588
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50569394
Nikkaji Number:J1.963.072B
Wikidata:Q72453580
Mol file:40932-43-2.mol

Synonyms:2-chloro-N-methylpyridin-3-amine;40932-43-2;2-Chloro-3-methylaminopyridine;2-Chloro-3-(methylamino)pyridine;2-chloro-N-methyl-3-pyridinamine;MFCD01646148;LacinileneC;2-chloro-3-(aminomethyl)pyridine;SCHEMBL4955823;2-chloropyridin-3-yl methylamine;DTXSID50569394;GAZKXXATBWGUHZ-UHFFFAOYSA-N;2-Chloro-N-methyl-pyridin-3-amine;3-Pyridinamine, 2-chloro-N-methyl-;2-chloranyl-N-methyl-pyridin-3-amine;AKOS005145856;DS-3973;SB75663;AC-23690;CS-0136675;F17445;EN300-1254577;A825350;AC-907/34117030

Suppliers and Price of 2-chloro-N-methylpyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-N-methylpyridin-3-amine
100mg
$ 90.00

SynQuest Laboratories
2-Chloro-3-methylaminopyridine 95%
250 mg
$ 408.00

SynQuest Laboratories
2-Chloro-3-methylaminopyridine 95%
1 g
$ 808.00

Matrix Scientific
2-Chloro-3-methylaminopyridine 97%
1g
$ 603.00

Crysdot
2-Chloro-N-methylpyridin-3-amine 95+%
5g
$ 353.00

Chemenu
2-chloro-N-methylpyridin-3-amine 95%
1g
$ 281.00

Chemenu
2-chloro-N-methylpyridin-3-amine 95%
100mg
$ 77.00

Chemenu
2-chloro-N-methylpyridin-3-amine 95%
250mg
$ 122.00

Chemcia Scientific
(2-Chloro-pyridin-3-yl)-methyl-amine 95%
1 G
$ 95.00

Biosynth Carbosynth
2-Chloro-3-methylaminopyridine
50 mg
$ 60.00

Total 40 raw suppliers

Chemical Property of 2-chloro-N-methylpyridin-3-amine

Chemical Property:

Vapor Pressure:0.021mmHg at 25°C
Refractive Index:1.597
Boiling Point:250.708 °C at 760 mmHg
Flash Point:105.425 °C
PSA：24.92000
Density:1.25 g/cm³
LogP:1.84970
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:142.0297759
Heavy Atom Count:9
Complexity:87.1

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-N-methylpyridin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(N=CC=C1)Cl

Technology Process of 2-chloro-N-methylpyridin-3-amine

There total 6 articles about 2-chloro-N-methylpyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 6298-19-7
2-chloro-3-aminopyridine

: 74-88-4
methyl iodide

: 40932-43-2
(2-chloro-pyridin-3-yl)-methyl-amine

Guidance literature:: 2-chloro-3-aminopyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 0 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -78 - 20 ℃; for 16h;

Reference yield: 85.0%

: tert-butyl (2-chloropyridin-3-yl)(methyl)carbamate

: 40932-43-2
(2-chloro-pyridin-3-yl)-methyl-amine

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 - 25 ℃; for 15h;

Reference yield:

: 209798-48-1
tert-butyl N-(2-chloro-3-pyridinyl)carbamate

: 40932-43-2
(2-chloro-pyridin-3-yl)-methyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 °C / Inert atmosphere

1.2: 2 h / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 3 h / Inert atmosphere

With sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol300359s