1-Cyclopropylpiperidin-4-one

Base Information

Chemical Name:1-Cyclopropylpiperidin-4-one
CAS No.:62813-01-8
Molecular Formula:C8H13NO
Molecular Weight:139.197
Hs Code.:2933399090
European Community (EC) Number:845-873-6
DSSTox Substance ID:DTXSID30585431
Nikkaji Number:J2.535.939I
Wikidata:Q72461095
Mol file:62813-01-8.mol

Synonyms:1-cyclopropylpiperidin-4-one;62813-01-8;1-Cyclopropyl-4-piperidinone;1-CYCLOPROPYL-4-PIPERIDONE;4-Piperidinone, 1-cyclopropyl-;MFCD07374375;1-CYCLOPROPYLTETRAHYDRO-4(1H)-PYRIDINONE;1-cyclopropyl-4-piperidon;N-cyclopropyl-4-piperidone;1-cyclopropylpiperidin-2-one;SCHEMBL121604;1-Cyclopropyl-piperidin-4-one;1-(Cyclopropyl)piperidin-4-one;DTXSID30585431;DTUJRJIWGWTNFQ-UHFFFAOYSA-N;AKOS000118068;AB39309;CS-W011041;LA-0813;SY020449;AM20100539;EN300-26516;A834012;J-504577;F8881-5235;Z223607160

Suppliers and Price of 1-Cyclopropylpiperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Cyclopropylpiperidin-4-one
100mg
$ 45.00

SynQuest Laboratories
1-Cyclopropylpiperidin-4-one
10 g
$ 159.00

SynQuest Laboratories
1-Cyclopropylpiperidin-4-one
5 g
$ 92.00

Matrix Scientific
1-Cyclopropyltetrahydro-4(1H)-pyridinone >95%
25g
$ 450.00

Matrix Scientific
1-Cyclopropyltetrahydro-4(1H)-pyridinone >95%
1g
$ 50.00

Matrix Scientific
1-Cyclopropyltetrahydro-4(1H)-pyridinone >95%
5g
$ 150.00

Crysdot
1-Cyclopropyl-4-piperidinone 95+%
25g
$ 210.00

Crysdot
1-Cyclopropyl-4-piperidinone 95+%
5g
$ 60.00

Crysdot
1-Cyclopropyl-4-piperidinone 95+%
10g
$ 105.00

Biosynth Carbosynth
1-Cyclopropylpiperidin-4-one
5 g
$ 112.00

Total 60 raw suppliers

Chemical Property of 1-Cyclopropylpiperidin-4-one

Chemical Property:

Vapor Pressure:0.053mmHg at 25°C
Melting Point:135-140°C(lit.)
Refractive Index:1.552
Boiling Point:234.271 °C at 760 mmHg
PKA:8.18±0.20(Predicted)
Flash Point:88.813 °C
PSA：20.31000
Density:1.151 g/cm³
LogP:0.75160
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:139.099714038
Heavy Atom Count:10
Complexity:141

Purity/Quality:

97% ^*data from raw suppliers

1-Cyclopropylpiperidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1N2CCC(=O)CC2
Uses 1-Cyclopropylpiperidin-4-one

Technology Process of 1-Cyclopropylpiperidin-4-one

There total 7 articles about 1-Cyclopropylpiperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.2%

: 41661-47-6
piperidin-4-one

: 4333-56-6,130561-87-4
cyclopropyl bromide

: 62813-01-8
1-cyclopropylpiperidin-4-one

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; for 6h; Reflux;

Reference yield: 67.0%

: 49683-17-2
3-[cyclopropyl-(2-ethoxycarbonyl-ethyl)-amino]-propionic acid ethyl ester

: 62813-01-8
1-cyclopropylpiperidin-4-one

Guidance literature:: 3-[cyclopropyl-(2-ethoxycarbonyl-ethyl)-amino]-propionic acid ethyl ester; With ethanol; sodium hydride; In tetrahydrofuran; for 24h; Heating / reflux;

With hydrogenchloride; water; for 5h; Heating / reflux;

With water; sodium hydride; pH=12;

Reference yield: 67.0%

: 49681-84-7
ethyl 1-cyclopropyl-4-oxopiperidine-3-carboxylate

: 62813-01-8
1-cyclopropylpiperidin-4-one

Guidance literature:: ethyl 1-cyclopropyl-4-oxopiperidine-3-carboxylate; With hydrogenchloride; water; for 5h; Reflux;

With sodium hydroxide; pH=12;
DOI:10.1021/jm900409x