C₂₄H₂₆Cl₂N₂O₄

Base Information

• Chemical Name: C₂₄H₂₆Cl₂N₂O₄
• CAS No.: 1430798-63-2
• Molecular Formula: C₂₄H₂₆Cl₂N₂O₄
• Molecular Weight: 477.387
• Mol file: 1430798-63-2.mol

Synonyms:C₂₄H₂₆Cl₂N₂O₄

Chemical Property of C₂₄H₂₆Cl₂N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₆Cl₂N₂O₄

There total 4 articles about C₂₄H₂₆Cl₂N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2'-(4,6-dichloro-5-methoxy-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (1221589-79-2) + C5H8INO (1430798-68-7) + C12H14INO2 (1430798-59-6) → C24H26Cl2N2O4 (1430798-63-2)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In 1,2-dimethoxyethane; water; at 90 ℃; for 2.5h; Inert atmosphere;

Reference yield:

(4,6-dichloro-5-methoxy-1,3-phenylene)bis(trimethylsilane) (1221589-81-6) → C24H26Cl2N2O4 (1430798-63-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Iodine monochloride / dichloromethane / 20 °C / Cooling with ice

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 24.08 h / 80 °C / Inert atmosphere; Schlenk technique

3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 2.5 h / 90 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; Iodine monochloride; potassium carbonate; In 1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide;

Reference yield:

2,6-dichloroanisole (1984-65-2) → C24H26Cl2N2O4 (1430798-63-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 3.5 h / -78 - -65 °C / Inert atmosphere; Schlenk technique

1.2: 1 h / -75 - -65 °C / Inert atmosphere; Schlenk technique

2.1: Iodine monochloride / dichloromethane / 20 °C / Cooling with ice

3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 24.08 h / 80 °C / Inert atmosphere; Schlenk technique

4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 2.5 h / 90 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; Iodine monochloride; potassium carbonate; lithium diisopropyl amide; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide;

upstream raw materials:

2,2'-(4,6-dichloro-5-methoxy-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

C₅H₈INO

C₁₂H₁₄INO₂

(4,6-dichloro-5-methoxy-1,3-phenylene)bis(trimethylsilane)

Downstream raw materials:

C₂₄H₂₄N₂O₄

deoxynyboquinone