N-(4-Ethylenedioxycylohexyl)-1-amino-2,2-diethoxyethane

Base Information

• Chemical Name: N-(4-Ethylenedioxycylohexyl)-1-amino-2,2-diethoxyethane
• CAS No.: 176492-83-4
• Molecular Formula: C14H27 N O4
• Molecular Weight: 273.373
• Hs Code.: 2932999099
• Mol file: 176492-83-4.mol

Synonyms:(2,2-Diethoxyethyl)(1,4-dioxaspiro[4.5]dec-8-yl)amine

Chemical Property of N-(4-Ethylenedioxycylohexyl)-1-amino-2,2-diethoxyethane

Chemical Property:

• PSA: 48.95000
• LogP: 1.27150

Purity/Quality:

99% ^*data from raw suppliers

(2,2-DIETHOXY-ETHYL)-(1,4-DIOXA-SPIRO[4.5]DEC-8-YL)-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-Ethylenedioxycylohexyl)-1-amino-2,2-diethoxyethane

There total 5 articles about N-(4-Ethylenedioxycylohexyl)-1-amino-2,2-diethoxyethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C14H25NO4 (1184301-08-3) → N-(2,2-diethoxyethyl)-4-aminocyclohexanone ethylene acetal (176492-83-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 12h;

DOI:10.1002/anie.201909518

Reference yield: 85.0%

cyclohexanedione monoethylene ketal (4746-97-8) + 2,2-diethoxy-ethanamine (645-36-3) → N-(2,2-diethoxyethyl)-4-aminocyclohexanone ethylene acetal (176492-83-4)

Guidance literature:

With sodium tris(acetoxy)borohydride; In dichloromethane; Inert atmosphere;

DOI:10.3390/molecules22050827

Reference yield:

cyclohexanedione monoethylene ketal (4746-97-8) → N-(2,2-diethoxyethyl)-4-aminocyclohexanone ethylene acetal (176492-83-4)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 4 h / 20 °C / Molecular sieve

2: sodium tetrahydroborate / methanol / 12 h / 20 °C

With sodium tetrahydroborate; In methanol; dichloromethane;

DOI:10.1002/anie.201909518

upstream raw materials:

cyclohexanedione monoethylene ketal

2,2-diethoxy-ethanamine

C₁₄H₂₅NO₄