7-Bromo-2-tetralone

Base Information

• Chemical Name: 7-Bromo-2-tetralone
• CAS No.: 132095-54-6
• Molecular Formula: C10H9BrO
• Molecular Weight: 225.085
• DSSTox Substance ID: DTXSID50395115
• Wikidata: Q72512823
• Mol file: 132095-54-6.mol

Synonyms:7-BROMO-2-TETRALONE;132095-54-6;7-bromo-3,4-dihydro-1H-naphthalen-2-one;7-bromo-3,4-dihydronaphthalen-2(1H)-one;2(1H)-Naphthalenone, 7-bromo-3,4-dihydro-;7-bromo-1,2,3,4-tetrahydronaphthalen-2-one;7-bromo-3,4-dihydro-2(1H)-Naphthalenone;2(1H)-Naphthalenone, 7-bromo-3,4-dihydro;SCHEMBL415637;DTXSID50395115;NCTYMQMYDHAKCE-UHFFFAOYSA-N;BCP11493;CS-B0104;MFCD04038486;AKOS015835919;AB17100;AS-65228;AM20020395;FT-0658061;7-bromanyl-3,4-dihydro-1H-naphthalen-2-one;EN300-379516;A806374;J-519121

Chemical Property of 7-Bromo-2-tetralone

Chemical Property:

• Vapor Pressure: 0.000344mmHg at 25°C
• Melting Point: 72-74 °C
• Refractive Index: 1.598
• Boiling Point: 319.195 °C at 760 mmHg
• Flash Point: 108.661 °C
• PSA: 17.07000
• Density: 1.511 g/cm³
• LogP: 2.50690
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 223.98368
• Heavy Atom Count: 12
• Complexity: 190

Purity/Quality:

99% ^*data from raw suppliers

7-Bromo-2-tetralone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(CC1=O)C=C(C=C2)Br

Technology Process of 7-Bromo-2-tetralone

There total 6 articles about 7-Bromo-2-tetralone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.7%

ethene (74-85-1) + 3-Bromophenylacetic acid (1878-67-7) → 7-bromo-2-tetralone (132095-54-6)

Guidance literature:

3-Bromophenylacetic acid; With oxalyl dichloride; In dichloromethane; at 0 ℃; for 2h; Reflux;

ethene; With aluminum (III) chloride; In dichloromethane; at -10 - -5 ℃; for 2h;

Reference yield: 71.1%

1,2,3,4-tetrahydronaphthalen-2-one (530-93-8) → 7-bromo-2-tetralone (132095-54-6)

Guidance literature:

1,2,3,4-tetrahydronaphthalen-2-one; aluminum (III) chloride; In dichloromethane; for 0.283333h;

With bromine; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 43.0%

ethene (74-85-1) + 2-(3-bromophenyl)acetyl chloride (98288-51-8) → 7-bromo-2-tetralone (132095-54-6)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at -5 - 0 ℃; for 3h;

upstream raw materials:

ethene

3-Bromophenylacetic acid

2-(3-bromophenyl)acetyl chloride

1,2,3,4-tetrahydronaphthalen-2-one