1-Aminohydantoin hydrochloride

Base Information

• Chemical Name: 1-Aminohydantoin hydrochloride
• CAS No.: 2827-56-7
• Molecular Formula: C3H6ClN3O2
• Molecular Weight: 151.553
• Hs Code.: 29332100
• Mol file: 2827-56-7.mol

Synonyms:2,4-Imidazolidinedione,1-amino-, monohydrochloride (9CI);Hydantoin, 1-amino-, hydrochloride (6CI,7CI,8CI);1-Amino-2,4-imidazolidinedione monohydrochloride;

Chemical Property of 1-Aminohydantoin hydrochloride

Chemical Property:

• Appearance/Colour: Pale yellow powder
• Vapor Pressure: 0.0119mmHg at 25°C
• Melting Point: 201-205 °C(lit.)
• Boiling Point: 256.8 °C at 760 mmHg
• Flash Point: 109.1 °C
• PSA: 75.43000
• LogP: 0.18090
• Storage Temp.: 0-6°C
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

99.0% ^*data from raw suppliers

Jag1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Nitrofuran. Reactant for synthesis of: Ectoparasiticidal drugs1 Skeletal muscle relaxants2Reactant for: Suzuki-Miyaura coupling3 Lymphoid specific tryosine phosphatase inhibitor4 Proteasome inhibition by peptide semicarbazones5 1-Aminohydantoin hydrochloride may be used as one of the reactants in the synthesis of (E)-1-(2-hydroxybenzylideneamino)imidazolidine-2,4-dione, dantrolene and dantrolene sodium.

Technology Process of 1-Aminohydantoin hydrochloride

There total 1 articles about 1-Aminohydantoin hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nitrofurantoin (67-20-9) → 1-aminohydantoin hydrochloride (2827-56-7)

Guidance literature:

With hydrogenchloride; In water; at 25 ℃; for 12h;

DOI:10.1021/acs.jafc.7b01050

Reference yield: 100.0%

C13H15NO5 + 1-aminohydantoin hydrochloride (2827-56-7) → C16H18N4O6

Guidance literature:

In methanol; at 20 ℃;

Reference yield: 95.0%

5-nitrofurane-2-carboxaldehyde (698-63-5) + 1-aminohydantoin hydrochloride (2827-56-7) → Nitrofurantoin (67-20-9)

Guidance literature:

With zirconium(IV) oxide; for 0.25h;

DOI:10.1039/c8gc01345d

upstream raw materials:

Nitrofurantoin

Downstream raw materials:

1-(4-acetylamino-benzylidenamino)-imidazolidine-2,4-dione

1-[5-(4-chloro-phenyl)-oxazol-2-ylmethyleneamino]-imidazolidine-2,4-dione

<<(2,4-dioxo-1-imidazolidinyl)imino>methyl>formic acid

N-(2,4-dioxo-imidazolidin-1-yl)-3-(4-fluoro-phenyl)-acrylamide

Refernces